Escherichia coli strain FWSEC0124

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0124 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It primarily resides in host-associated habitats and is mesophilic, with an optimal growth temperature of 37°C. FWSEC0124 has a notable biotic relationship, being free-living and capable of infecting a wide variety of hosts, including Homo sapiens, Gallus gallus, Bos taurus, Sus scrofa, Canis lupus familiaris, and many others, encompassing several taxa such as mammals, birds, and even plants like Solanum lycopersicum and Brassica oleracea var. italica. This wide range of hosts indicates its ecological versatility. The pathogenicity of E. coli strain FWSEC0124 in humans is significant, as it is associated with numerous health effects, including urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and foodborne illnesses. The strain can lead to severe conditions such as hemolytic uremic syndrome (HUS), peritonitis, and even complications like renal failure and septicemia. The diversity of hosts and the range of diseases caused by FWSEC0124 highlight its ecological adaptability and potential public health impact. This strain exemplifies the importance of monitoring bacterial pathogens in both human health and veterinary contexts, given their capability to cross species barriers and cause serious infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0124

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0124
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0124 plasmid unnamed5

Gene Summary

Adenine Count

1231719 bp

Thymine Count

1238438 bp

Guanine Count

1285393 bp

Cytosine Count

1257336 bp

Genome Length

5023556 bp

Protein-coding Genes

4506 genes

Non-Coding Genes

351 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transcription antitermination factor nusbC9Z74_12220Not AvailableNegative2535550 - 253596915689.9
6,7-dimethyl-8-ribityllumazine synthaseC9Z74_12225Not AvailableNegative2535989 - 253645916157.4
bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase ribdC9Z74_12230Not AvailableNegative2536548 - 253765140340.7
transcriptional regulator nrdrC9Z74_12235Not AvailableNegative2537655 - 253810417229.9
duf3251 domain-containing proteinC9Z74_12240Not AvailablePositive2538255 - 253879419561.5
nucleoside-specific channel-forming protein tsxC9Z74_12245Not AvailablePositive2539093 - 253997733590.6
hnh nuclease family proteinC9Z74_12250Not AvailableNegative2540154 - 254050113364.7
protein translocase subunit secfC9Z74_12255Not AvailableNegative2540630 - 254160135384.6
protein translocase subunit secdC9Z74_12260Not AvailableNegative2541612 - 254345966636.3
preprotein translocase subunit yajcC9Z74_12265Not AvailableNegative2543487 - 254381911887.9

Displaying genes 2701 – 2710 of 4862 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total