Escherichia coli strain FWSEC0116

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0116 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism and possesses flagella, enabling mobility. It typically exists in pairs or singles and thrives at an optimal temperature of 37°C, categorizing it as mesophilic. This strain is free-living and primarily found in host-associated environments, with a diverse range of hosts including Homo sapiens, Gallus gallus, Bos taurus, and various other vertebrates and invertebrates. FWSEC0116 is associated with several health effects, particularly in humans, where it can cause urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis among other conditions. The strain has been linked to severe health issues such as hemolytic uremic syndrome (HUS), septicemia, and foodborne infections. Notably, it can lead to complications like renal failure and colorectal cancer, indicating its significant pathogenic potential. The diverse host range of FWSEC0116 suggests that it plays a role in both human and animal health, highlighting its ecological versatility. This strain's ability to adapt to various hosts and environments underlines the importance of monitoring E. coli strains for public health, especially in relation to zoonotic transmission and food safety. Understanding the pathogenicity and transmission dynamics of FWSEC0116 provides insights into managing infections and preventing outbreaks associated with this bacterium.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0116

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0116
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0116 plasmid unnamed2

Gene Summary

Adenine Count

1215642 bp

Thymine Count

1213841 bp

Guanine Count

1244280 bp

Cytosine Count

1257279 bp

Genome Length

4938066 bp

Protein-coding Genes

4425 genes

Non-Coding Genes

360 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Protein 40a (acetate kinase superfamily domain)C9Z66_18180Not AvailableNegative3764089 - 376495231621.8
Repressor proteinC9Z66_18185Not AvailableNegative3765019 - 376570825493.6
Helix-turn-helix domain-containing proteinC9Z66_18190Not AvailablePositive3765813 - 37660438150.94
Cii proteinC9Z66_18195Not AvailablePositive3766113 - 376665220136.2
Replication protein oC9Z66_18200Not AvailablePositive3766739 - 376766834566.1
Replication protein pC9Z66_18205Not AvailablePositive3767665 - 376836626519.9
Ren proteinC9Z66_18210Not AvailablePositive3768363 - 376866511131.6
Putative quaternary ammonium compound-resistance protein qaceC9Z66_18215Not AvailablePositive3768733 - 376906511901.0
hypothetical proteinC9Z66_18220Not AvailablePositive3769157 - 37692644223.45
Gp53C9Z66_18225Not AvailablePositive3769322 - 377084857516.1

Displaying genes 221 – 230 of 4786 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total