Escherichia coli strain FWSEC0086

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0086 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. It is motile, equipped with flagella, and typically found in pairs or singles. This strain is mesophilic, with an optimal growth temperature of 37°C, which aligns with the body temperature of its primary host, Homo sapiens, among others. FWSEC0086 is free-living but is associated with a wide variety of hosts, including mammals like Bos taurus (cattle) and Felis catus (domestic cats), as well as birds such as Gallus gallus (chickens) and reptiles like Python regius. This diverse host range indicates its ecological adaptability and potential for zoonotic transmission. The strain is implicated in numerous health effects, particularly in humans, where it is associated with urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemolytic uremic syndrome (HUS) and neonatal meningitis. The breadth of health issues linked to FWSEC0086 underscores its pathogenic potential and highlights the importance of monitoring and managing its presence in both clinical and environmental contexts. Given its wide array of hosts and the significant health effects it can cause, E. coli strain FWSEC0086 illustrates the complex interplay between bacterial pathogens and their hosts, emphasizing the need for ongoing research into its pathogenic mechanisms and the ecological factors that influence its transmission and virulence.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0086

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0086
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0086 plasmid unnamed2

Gene Summary

Adenine Count

1222231 bp

Thymine Count

1214913 bp

Guanine Count

1247590 bp

Cytosine Count

1260839 bp

Genome Length

4953373 bp

Protein-coding Genes

4531 genes

Non-Coding Genes

272 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
molybdopterin-dependent oxidoreductase mo/fe-s-binding subunitC9Z36_01025Not AvailablePositive212609 - 215479103525.0
xanthine permease xanqC9Z36_01030Not AvailablePositive215644 - 21704449111.5
Ncrna_class:otherNot AvailableNot AvailablePositive215815 - 215940Not Available
guanine deaminaseC9Z36_01035Not AvailablePositive217062 - 21837850102.8
guanine/hypoxanthine permease ghxqC9Z36_01040Not AvailablePositive218414 - 21978146761.0
oxidoreductaseC9Z36_01045Not AvailableNegative219817 - 22030517514.3
oxidoreductase (fe-s)-binding subunitC9Z36_01050Not AvailableNegative220305 - 22222469077.8
uric acid transporter uactC9Z36_01055Not AvailablePositive222660 - 22410851761.4
hypothetical proteinC9Z36_01060Not AvailablePositive224110 - 2242354757.28
hypothetical proteinC9Z36_01065Not AvailableNegative224232 - 2243032617.29

Displaying genes 421 – 430 of 4805 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total