Escherichia coli strain FWSEC0080

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0080 is a Gram-negative bacterium characterized by its rod shape and mobility, facilitated by the presence of flagella. It is classified as a facultative anaerobe, capable of thriving in both aerobic and anaerobic conditions, with an optimal growth temperature of 37°C, placing it within the mesophilic temperature range. This strain is associated with a wide variety of hosts, including Homo sapiens, Gallus gallus, Bos taurus, and various other mammals and vertebrates, indicating its ecological adaptability. Biologically, E. coli FWSEC0080 is noteworthy for its health effects on humans, where it is implicated in a range of serious conditions such as urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis, among others. The strain is linked to multiple pathologies, including diarrhea, septicemia, and complications leading to hemolytic uremic syndrome (HUS). Its pathogenicity is significant, particularly in human health, where infections can lead to severe clinical outcomes, including renal failure and systemic diseases. The free-living nature of E. coli FWSEC0080 suggests its potential for environmental persistence, enabling interaction with various hosts and contributing to the epidemiology of foodborne infections. As such, understanding its diverse biotic relationships and pathogenic mechanisms is crucial for public health, particularly in controlling and preventing outbreaks associated with this strain in both human and veterinary contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0080

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0080
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0080 plasmid unnamed1

Gene Summary

Adenine Count

1274467 bp

Thymine Count

1275855 bp

Guanine Count

1301432 bp

Cytosine Count

1296278 bp

Genome Length

5159557 bp

Protein-coding Genes

4691 genes

Non-Coding Genes

411 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
flagellar export chaperone flisC9Z30_00040Not AvailableNegative5121 - 553115019.2
flagellar filament capping protein flidC9Z30_00045Not AvailableNegative5547 - 696248860.4
flic/fljb family flagellinC9Z30_00050Not AvailablePositive7208 - 853946397.4
rna polymerase sigma factor fliaC9Z30_00055Not AvailablePositive8859 - 957827522.8
flagella biosynthesis regulatory protein flizC9Z30_00060Not AvailablePositive9624 - 1017521468.8
cystine abc transporter substrate-binding proteinC9Z30_00065Not AvailablePositive10263 - 1106328996.8
d-cysteine desulfhydraseC9Z30_00070Not AvailablePositive11168 - 1215435155.4
amino acid abc transporter permeaseC9Z30_00075Not AvailablePositive12169 - 1283724802.7
l-cystine abc transporter atp-binding protein yeccC9Z30_00080Not AvailablePositive12834 - 1358627677.7
transcriptional regulator sdiaC9Z30_00085Not AvailablePositive13816 - 1453828050.7

Displaying genes 411 – 420 of 5105 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total