Escherichia coli strain FWSEC0050

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0050 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This strain is mesophilic, with an optimal growth temperature of 37°C, and typically exists in pairs or as single cells. FWSEC0050 is primarily host-associated, indicating its ecological niche involves various hosts including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and a diverse range of other animals and plants. This broad host range encompasses mammals, reptiles, insects, and even some flora, such as Solanum lycopersicum (tomato) and Brassica oleracea var. italica (broccoli). The strain is known for its pathogenicity in humans, with associations to numerous health effects, including urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis, among others. The wide array of diseases linked to FWSEC0050 suggests that it plays a significant role in both clinical and environmental contexts, impacting human health and agriculture. The free-living nature of FWSEC0050, combined with its versatility across various hosts, highlights its potential ecological impact. Its ability to cause diverse health issues may influence host populations and ecosystems, emphasizing the importance of understanding such strains in microbiological studies and public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0050

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0050
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0050 plasmid unnamed3

Gene Summary

Adenine Count

1229981 bp

Thymine Count

1225387 bp

Guanine Count

1242468 bp

Cytosine Count

1255755 bp

Genome Length

4968186 bp

Protein-coding Genes

4560 genes

Non-Coding Genes

189 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glycine cleavage system transcriptional repressorC9Z01_21850Not AvailablePositive4465158 - 446573020769.8
thioredoxin-dependent thiol peroxidaseC9Z01_21855Not AvailablePositive4465730 - 446620017634.9
4fe-4s dicluster domain-containing proteinC9Z01_21860Not AvailablePositive4466453 - 446705521620.9
uroporphyrinogen decarboxylaseC9Z01_21870Not AvailablePositive4467668 - 446873239250.4
deoxyribonuclease vC9Z01_21875Not AvailablePositive4468742 - 446941324673.9
duf416 family proteinC9Z01_21880Not AvailablePositive4469456 - 447004622599.9
dna-binding protein hu-alphaC9Z01_21885Not AvailablePositive4470233 - 44705059535.51
duf1481 domain-containing proteinC9Z01_21890Not AvailablePositive4470518 - 447121326318.9
zinc resistance-associated proteinC9Z01_21895Not AvailableNegative4471215 - 447164015200.3
two-component sensor histidine kinaseC9Z01_21900Not AvailablePositive4471878 - 447327551034.9

Displaying genes 4311 – 4320 of 4756 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total