Escherichia coli strain FWSEC0043

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0043 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe. It typically exists in pairs or singly and possesses flagella, enabling mobility. This strain is mesophilic, with an optimal growth temperature of 37°C, which is conducive to its survival in warm-blooded hosts. FWSEC0043 is notably associated with a diverse range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other mammals, birds, and even some plant species like Solanum lycopersicum (tomato) and Brassica oleracea var. italica (broccoli). This broad host range suggests a versatile ecological adaptability and highlights the strain's potential to influence multiple ecosystems. The strain is implicated in numerous health conditions, particularly in humans, where it is associated with urinary tract infections (UTIs), gastrointestinal infections, and more severe health issues such as neonatal meningitis and hemolytic uremic syndrome (HUS). Its pathogenicity is significant, demonstrating its ability to cause both localized and systemic infections, which can have severe health repercussions, including renal failure and septicemia. In terms of ecological insight, the ability of FWSEC0043 to inhabit various environments and affect multiple host species underscores its role in the microbiome and its potential impact on health across different organisms. Its presence in both human and animal hosts illustrates the interconnectedness of health within ecosystems, further emphasizing the importance of monitoring such strains in public health and veterinary contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0043

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0043
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0043 plasmid unnamed2

Gene Summary

Adenine Count

1285098 bp

Thymine Count

1286106 bp

Guanine Count

1307450 bp

Cytosine Count

1301511 bp

Genome Length

5192615 bp

Protein-coding Genes

4747 genes

Non-Coding Genes

247 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dihydrolipoyl dehydrogenaseC9Y94_00440Not AvailableNegative94184 - 9560850691.4
dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complexC9Y94_00445Not AvailableNegative95933 - 9782566129.8
pyruvate dehydrogenase (acetyl-transferring), homodimeric typeC9Y94_00450Not AvailableNegative97840 - 10050399674.1
pyruvate dehydrogenase complex repressorC9Y94_00455Not AvailableNegative100664 - 10142829427.2
aromatic amino acid transporter aropC9Y94_00460Not AvailablePositive101972 - 10334249547.9
protein ampeC9Y94_00465Not AvailableNegative103385 - 10423932123.9
1,6-anhydro-n-acetylmuramyl-l-alanine amidase ampdC9Y94_00470Not AvailableNegative104236 - 10478720495.1
carboxylating nicotinate-nucleotide diphosphorylaseC9Y94_00475Not AvailablePositive104875 - 10576832774.0
prepilin peptidase-dependent pilinC9Y94_00480Not AvailablePositive105971 - 10641115588.7
type ii secretion system protein gspeC9Y94_00485Not AvailablePositive106421 - 10780650598.3

Displaying genes 301 – 310 of 5002 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total