Escherichia coli strain FWSEC0024

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0024 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe. It is capable of mobility, possessing flagella, and typically resides in host-associated environments. This strain shows a preference for an optimal growth temperature of 37°C, indicating its mesophilic nature. FWSEC0024 has a diverse set of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other vertebrates and invertebrates such as Canis lupus familiaris (domestic dogs), Felis catus (domestic cats), and Apis mellifera (honeybees). This broad host range underscores its ecological versatility and adaptability. The strain is known to have significant health impacts on humans, leading to a variety of conditions ranging from urinary tract infections (UTIs) and gastrointestinal infections to more severe diseases such as neonatal meningitis and hemolytic uremic syndrome (HUS). These health effects highlight the strain’s pathogenicity, particularly in human hosts. Given its free-living biotic relationship and extensive host interactions, FWSEC0024 exemplifies the complex dynamics between bacteria and their environments, including their role in human health and disease. Understanding the pathogenic mechanisms of this strain can be crucial for developing targeted interventions to mitigate its associated health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0024

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0024
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0024 plasmid unnamed4

Gene Summary

Adenine Count

1326330 bp

Thymine Count

1315350 bp

Guanine Count

1331351 bp

Cytosine Count

1345189 bp

Genome Length

5334330 bp

Protein-coding Genes

4993 genes

Non-Coding Genes

330 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinC9Y77_02260Not AvailablePositive472115 - 47239010287.2
multidrug efflux transporter periplasmic adaptor subunit mdtnC9Y77_02265Not AvailablePositive472409 - 47344036910.3
multidrug efflux transporter permease subunit mdtoC9Y77_02270Not AvailablePositive473440 - 47549176208.2
multidrug efflux transporter outer membrane subunit mdtpC9Y77_02275Not AvailablePositive475488 - 47695453442.3
formate dehydrogenase subunit alphaC9Y77_02280Not AvailablePositive477152 - 47929979228.1
sel1 repeat family proteinC9Y77_02285Not AvailablePositive479393 - 48008225080.4
glutamate/aspartate:proton symporter gltpC9Y77_02290Not AvailableNegative480160 - 48147347107.0
heme lyase nrfefg subunit nrfgC9Y77_02295Not AvailableNegative481815 - 48241122755.4
heme lyase nrfefg subunit nrffC9Y77_02300Not AvailableNegative482408 - 48279114543.0
heme lyase ccmf/nrfe family subunitC9Y77_02305Not AvailableNegative482784 - 48450263641.2

Displaying genes 741 – 750 of 5327 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total