Fusobacterium nucleatum strain OH5060

Fusobacterium nucleatum strain OH5060 is a Gram-negative, rod-shaped bacterium classified as a chemoheterotroph. This strain exhibits a typical cell arrangement in pairs and is characterized by its anaerobic oxygen requirement. It does not possess mobility and has a flagella presence, indicating potential for movement in environments where it may be relevant. The optimal growth temperature for F. nucleatum OH5060 is 37°C, placing it within the mesophilic temperature range. This strain is free-living and associated with hosts such as Homo sapiens and Oryctolagus cuniculus. The bacterium contains one replicon and has a double membrane structure. Fusobacterium nucleatum is notable for its pathogenicity, particularly in humans, where it is linked to several health issues, including colorectal cancer, Lemierre's syndrome, gingival diseases, and dental infections. Its carcinogenic properties and association with chronic oral and intestinal diseases underscore its significance in human health. The presence of this bacterium in the oral and intestinal microbiomes reflects its ecological role, highlighting the complex interactions between host organisms and their microbiota. Understanding the implications of F. nucleatum strain OH5060 in health and disease could provide insights into microbial management strategies, particularly in clinical settings where its pathogenic effects are of concern.