Tannerella forsythia strain OH1426_COT-023

Tannerella forsythia strain OH1426_COT-023 is a Gram-negative, anaerobic bacterium primarily found in the gingival sulci, as well as in subgingival and supragingival dental biofilms and subgingival plaque. This strain is specifically associated with human hosts (Homo sapiens) and is implicated in significant oral health issues, notably periodontitis and peri-implantitis. The bacterium has a single replicon, which is characteristic of its genetic organization. Its pathogenicity is well-documented in relation to periodontal diseases, indicating its role in the breakdown of periodontal tissue and contributing to the inflammatory processes associated with these conditions. The habitat of Tannerella forsythia underscores its ecological niche within the oral cavity, where it interacts with various other microbial species in dental biofilms. The anaerobic nature of this organism allows it to thrive in oxygen-poor environments, such as those found in subgingival plaque, which supports its role in periodontal disease development. Understanding the characteristics and behavior of Tannerella forsythia strain OH1426_COT-023 is crucial for developing therapeutic strategies aimed at managing periodontitis and peri-implantitis. By targeting this organism and its interactions within the complex oral microbiome, it may be possible to improve oral health outcomes for affected individuals.