Helicobacter pylori strain 1057

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 1057 is a microaerophilic, gram-negative bacterium characterized by its spirilla shape and presence of flagella. This organism is typically found in singles and has a mesophilic optimal growth temperature of 37°C. Notably, it possesses two membranes and a single replicon. H. pylori strain 1057 is primarily associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), Aves (birds), and other mammalian and primate species. Its biotic relationship is described as free living, suggesting a significant ecological versatility. This strain is known for its pathogenic effects in humans, being linked to a range of gastrointestinal diseases. These include chronic gastric inflammation, gastric ulcers, and various forms of gastric cancer, such as adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. Other health effects attributed to H. pylori strain 1057 encompass functional dyspepsia, atrophic gastritis, and gastrointestinal diseases, highlighting its role as a significant contributor to gastric pathology. The presence of H. pylori in diverse hosts may indicate its ecological adaptability and potential for zoonotic transmission. This adaptability may also facilitate its survival in various environments, which could contribute to its widespread prevalence and impact on human health. The strain's association with serious health conditions underscores the importance of understanding its biology and ecological interactions to develop effective prevention and treatment strategies for related diseases.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 1057

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 1057
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 1057 scaffold44.1, whole genome shotgun

Gene Summary

Adenine Count

513302 bp

Thymine Count

515254 bp

Guanine Count

328529 bp

Cytosine Count

324989 bp

Genome Length

1685370 bp

Protein-coding Genes

1533 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
septum site-determining protein mindEGW01_00085Not AvailablePositive14016 - 1482229379.9
cell division topological specificity factor mineEGW01_00090Not AvailablePositive14819 - 150528892.88
dna-protecting protein dpraEGW01_00095Not AvailablePositive15059 - 1585929824.4
holliday junction resolvase ruvxEGW01_00100Not AvailablePositive15856 - 1626015345.8
hypothetical proteinEGW01_00110Not AvailablePositive17027 - 1736513651.5
hypothetical proteinEGW01_00115Not AvailablePositive17349 - 1790921821.8
lysozymeEGW01_00120Not AvailablePositive17966 - 181727836.3
lysozymeEGW01_00125Not AvailablePositive18166 - 1842610135.6
Ncrna_class:rnase_p_rnaNot AvailableNot AvailablePositive18311 - 18626Not Available
hypothetical proteinEGW01_00150Not AvailablePositive20313 - 2109528517.1

Displaying genes 21 – 30 of 1578 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total