Helicobacter pylori strain 1071

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 1071 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and presence of flagella. This strain is predominantly found in various host-associated environments, including Homo sapiens (humans), Gallus gallus (domestic chickens), Aves (birds), and several mammalian species. It exhibits a single cell arrangement and has a mesophilic temperature range, with an optimal growth temperature of 37°C. H. pylori strain 1071 contains one replicon and is encased within two membranes, typical of its Gram-negative classification. It is capable of free-living biotic interactions within its host environments. This strain has significant health implications, being associated with chronic gastric inflammation, gastric ulcers, and various forms of gastric cancer, including adenocarcinoma and non-cardia carcinomas. Other health effects linked to this bacterium include gastritis, gastroesophageal reflux disease (GERD), and functional dyspepsia. Its pathogenicity in humans is well-documented, with evidence showing a direct correlation between H. pylori infection and the onset of several gastrointestinal diseases. The ecological role of H. pylori strain 1071 highlights its complex relationship with its hosts, where it can elicit both asymptomatic responses and severe pathogenic conditions. Understanding its behavior and impact on human health is crucial for developing effective treatment strategies and public health measures related to gastric diseases.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 1071

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 1071
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 1071 scaffold23.1, whole genome shotgun

Gene Summary

Adenine Count

504947 bp

Thymine Count

507071 bp

Guanine Count

328338 bp

Cytosine Count

318495 bp

Genome Length

1660584 bp

Protein-coding Genes

1486 genes

Non-Coding Genes

44 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinEGV99_00400Not AvailablePositive69713 - 7006314047.5
urease accessory protein uredEGV99_00410Not AvailableNegative72578 - 7337529906.2
urease accessory protein uregEGV99_00415Not AvailableNegative73375 - 7397421956.6
urease accessory protein urefEGV99_00420Not AvailableNegative74003 - 7477328749.7
urease accessory protein ureeEGV99_00425Not AvailableNegative74797 - 7530919394.7
acid-activated urea channelEGV99_00430Not AvailableNegative75311 - 7589821655.6
urease subunit betaEGV99_00435Not AvailableNegative76090 - 7779961687.2
urease subunit alphaEGV99_00440Not AvailableNegative77803 - 7851926541.1
Trna-valNot AvailableNot AvailablePositive78787 - 78862Not Available
lipoprotein signal peptidaseEGV99_00450Not AvailableNegative78881 - 7935417897.4

Displaying genes 71 – 80 of 1530 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total