Helicobacter pylori strain 1071

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 1071 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and presence of flagella. This strain is predominantly found in various host-associated environments, including Homo sapiens (humans), Gallus gallus (domestic chickens), Aves (birds), and several mammalian species. It exhibits a single cell arrangement and has a mesophilic temperature range, with an optimal growth temperature of 37°C. H. pylori strain 1071 contains one replicon and is encased within two membranes, typical of its Gram-negative classification. It is capable of free-living biotic interactions within its host environments. This strain has significant health implications, being associated with chronic gastric inflammation, gastric ulcers, and various forms of gastric cancer, including adenocarcinoma and non-cardia carcinomas. Other health effects linked to this bacterium include gastritis, gastroesophageal reflux disease (GERD), and functional dyspepsia. Its pathogenicity in humans is well-documented, with evidence showing a direct correlation between H. pylori infection and the onset of several gastrointestinal diseases. The ecological role of H. pylori strain 1071 highlights its complex relationship with its hosts, where it can elicit both asymptomatic responses and severe pathogenic conditions. Understanding its behavior and impact on human health is crucial for developing effective treatment strategies and public health measures related to gastric diseases.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 1071

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 1071
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 1071 scaffold23.1, whole genome shotgun

Gene Summary

Adenine Count

504947 bp

Thymine Count

507071 bp

Guanine Count

328338 bp

Cytosine Count

318495 bp

Genome Length

1660584 bp

Protein-coding Genes

1486 genes

Non-Coding Genes

44 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
competence protein combEGV99_00115Not AvailablePositive16763 - 1704410526.4
competence protein combEGV99_00120Not AvailablePositive17044 - 1730710034.7
virb4 family type iv secretion/conjugal transfer atpaseEGV99_00125Not AvailablePositive17309 - 1967290184.8
Ncrna_class:srp_rnaNot AvailableNot AvailablePositive19703 - 19800Not Available
hypothetical proteinEGV99_00135Not AvailablePositive19905 - 2131453508.9
chemotaxis signal transduction protein chevEGV99_00140Not AvailablePositive21418 - 2238336548.2
carboxynorspermidine decarboxylaseEGV99_00145Not AvailablePositive22380 - 2359745852.0
lipid a 1-phosphatase lpxeEGV99_00150Not AvailableNegative23607 - 2417921122.7
phosphoethanolamine--lipid a transferase eptaEGV99_00155Not AvailableNegative24190 - 2576159084.2
outer membrane proteinEGV99_00165Not AvailableNegative26422 - 2849474997.7

Displaying genes 21 – 30 of 1530 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total