Enterococcus faecalis strain EF5152

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecalis strain EF5152 is a Gram-positive, non-motile coccus that functions as a facultative anaerobe, utilizing organic compounds as a chemoorganotrophic energy source. This strain is mesophilic, with an optimal growth temperature of 37°C, which aligns with the human body temperature, suggesting its adaptation to thrive in warm-blooded hosts. E. faecalis strain EF5152 has a single membrane and one replicon, indicating a simple cellular structure typical of many bacteria. Its biotic relationship is free-living, allowing it to inhabit diverse environments, including the gastrointestinal tracts of various hosts. Notably, this strain has been identified in numerous species, including Homo sapiens, Gallus gallus (chickens), and several mammals and fish, highlighting its ecological versatility. This strain is associated with multiple health effects in humans, including bacteremia, urinary tract infections (UTIs), endocarditis, and various other infections affecting different body parts. Its pathogenicity is particularly concerning in nosocomial (hospital-acquired) infections, as it can cause severe conditions such as septicemia and infective endocarditis. E. faecalis is also implicated in infections in surgical sites and dental abscesses, indicating its potential to thrive in both community and healthcare settings. The diverse habitat and broad host range of Enterococcus faecalis strain EF5152, combined with its significant pathogenic potential, underline the importance of monitoring this organism in clinical and environmental contexts to mitigate its impact on public health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecalis
Strainstrain EF5152

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Enterococcus faecalis strain EF5152
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementChains
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Enterococcus faecalis strain EF5152 EF5152_Contig105, whole genome

Gene Summary

Adenine Count

956946 bp

Thymine Count

952450 bp

Guanine Count

581379 bp

Cytosine Count

574897 bp

Genome Length

3073366 bp

Protein-coding Genes

2886 genes

Non-Coding Genes

263 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinaseEG860_07315Not AvailableNegative1430808 - 143163829258.1
thiamine phosphate synthaseEG860_07320Not AvailableNegative1431635 - 143227022881.9
hydroxyethylthiazole kinaseEG860_07325Not AvailableNegative1432267 - 143308529687.6
energy coupling factor transporter s component thiwEG860_07330Not AvailableNegative1433069 - 143359919679.0
ybab/ebfc family nucleoid-associated proteinEG860_07335Not AvailableNegative1433934 - 143424811652.3
dna polymerase iii subunit gamma/tauEG860_07340Not AvailableNegative1434269 - 143602965750.1
udp-glucose--hexose-1-phosphate uridylyltransferaseEG860_07345Not AvailableNegative1436101 - 143731545465.0
udp-glucose 4-epimerase galeEG860_07350Not AvailableNegative1437332 - 143832436380.1
duf3042 family proteinEG860_07355Not AvailablePositive1438592 - 14387596089.71
oxidoreductaseEG860_07360Not AvailableNegative1438922 - 144076069271.5

Displaying genes 1591 – 1600 of 3150 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
EndophthalmitisCausesPMC10638747
Refractory apical periodontitisCausesPMC11307051
Infections in various body parts such as urinary tract, intra-abdomen and pelvic regions, surgical sites and oral cavityCausesPMC11307051
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Urinary tract infectionsCausesPMC11784074
MastitisCausesPMC13343983
PyelonephritisCausesPMC4308012
Various infectionsCausesPMC5109407
MeningitisCausesPMC5109407

Displaying health effects 1 – 10 of 47 in total