Escherichia coli strain PNUSAE019721

Escherichia coli strain PNUSAE019721 is a Gram-negative, facultative anaerobic bacterium characterized by its rod shape and mobility, attributed to the presence of flagella. This strain is primarily host-associated, with an optimal growth temperature of 37°C, fitting within the mesophilic temperature range. It comprises a single replicon and is surrounded by a double membrane. The biotic relationships of strain PNUSAE019721 indicate it is free-living, yet it has a wide array of hosts, including Homo sapiens, various domesticated animals such as Gallus gallus (chickens) and Bos taurus (cattle), as well as plants like Solanum lycopersicum (tomatoes) and Brassica oleracea var. italica (broccoli). This diverse host range suggests that E. coli PNUSAE019721 could play different roles in various ecological contexts, from symbiotic relationships in the gut to potential pathogenic interactions. Clinically, this strain is implicated in numerous health issues, particularly in humans. It is associated with urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and several severe conditions such as bloody diarrhea and hemolytic uremic syndrome (HUS). The pathogenic effects can lead to serious complications, including renal failure and septicemia. The extensive health impacts of E. coli PNUSAE019721 highlight its significance in both clinical microbiology and public health, underscoring the need for monitoring and understanding its behavior in both human and animal hosts to mitigate its pathogenic potential.