Escherichia coli strain CVM N17EC0248

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain CVM N17EC0248 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. It is motile, possessing flagella, and typically arranges itself in pairs or singles. This strain is mesophilic, with an optimal growth temperature of 37°C. CVM N17EC0248 is host-associated and shows a broad range of potential hosts, including Homo sapiens (humans), various mammals such as Bos taurus (cattle), Sus scrofa (pigs), and domestic animals like Canis lupus familiaris (dogs) and Felis catus (cats). It is also associated with avian species and some plant hosts like Solanum lycopersicum (tomato) and Brassica oleracea var. italica (broccoli). This diverse biotic relationship suggests that CVM N17EC0248 can survive in various ecological niches, both in animals and the environment. The strain is known for its pathogenicity in humans, linked to numerous health effects including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemorrhagic colitis and hemolytic uremic syndrome (HUS). This highlights its potential as a significant concern in public health due to its role in foodborne illnesses and clinical infections. The ability of CVM N17EC0248 to inhabit multiple hosts and its association with various diseases underscores its ecological versatility and adaptability. Understanding its interactions within different ecological contexts can provide insights into its pathogenic mechanisms and inform strategies for managing infections it may cause.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain CVM N17EC0248

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain CVM N17EC0248
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain CVM N17EC0248

Gene Summary

Adenine Count

1337776 bp

Thymine Count

1322231 bp

Guanine Count

1343905 bp

Cytosine Count

1380785 bp

Genome Length

5389732 bp

Protein-coding Genes

4773 genes

Non-Coding Genes

415 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
adenylyl-sulfate kinaseD9E35_18785Not AvailableNegative3933809 - 393441422322.7
sulfate adenylyltransferase subunit cysnD9E35_18790Not AvailableNegative3934414 - 393584152649.6
sulfate adenylyltransferase subunit 2D9E35_18795Not AvailableNegative3935843 - 393675135190.3
aminopeptidaseD9E35_18800Not AvailablePositive3937003 - 393804037869.4
type i-e crispr-associated endoribonuclease cas2D9E35_18805Not AvailableNegative3938613 - 393890611004.4
type i-e crispr-associated endonuclease cas1D9E35_18810Not AvailableNegative3938903 - 393982633425.7
type i-e crispr-associated protein cas6/cse3/caseD9E35_18815Not AvailableNegative3939823 - 394047324829.8
type i-e crispr-associated protein cas5/casdD9E35_18820Not AvailableNegative3940455 - 394120128630.0
type i-e crispr-associated protein cas7/cse4/cascD9E35_18825Not AvailableNegative3941212 - 394226738372.6
type i-e crispr-associated protein cse2/casbD9E35_18830Not AvailableNegative3942279 - 394281820602.6

Displaying genes 3771 – 3780 of 5190 in total

Metabolites

4691 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4691 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total