Escherichia coli strain CVM N17EC0248

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain CVM N17EC0248 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. It is motile, possessing flagella, and typically arranges itself in pairs or singles. This strain is mesophilic, with an optimal growth temperature of 37°C. CVM N17EC0248 is host-associated and shows a broad range of potential hosts, including Homo sapiens (humans), various mammals such as Bos taurus (cattle), Sus scrofa (pigs), and domestic animals like Canis lupus familiaris (dogs) and Felis catus (cats). It is also associated with avian species and some plant hosts like Solanum lycopersicum (tomato) and Brassica oleracea var. italica (broccoli). This diverse biotic relationship suggests that CVM N17EC0248 can survive in various ecological niches, both in animals and the environment. The strain is known for its pathogenicity in humans, linked to numerous health effects including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemorrhagic colitis and hemolytic uremic syndrome (HUS). This highlights its potential as a significant concern in public health due to its role in foodborne illnesses and clinical infections. The ability of CVM N17EC0248 to inhabit multiple hosts and its association with various diseases underscores its ecological versatility and adaptability. Understanding its interactions within different ecological contexts can provide insights into its pathogenic mechanisms and inform strategies for managing infections it may cause.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain CVM N17EC0248

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain CVM N17EC0248
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain CVM N17EC0248

Gene Summary

Adenine Count

1337776 bp

Thymine Count

1322231 bp

Guanine Count

1343905 bp

Cytosine Count

1380785 bp

Genome Length

5389732 bp

Protein-coding Genes

4773 genes

Non-Coding Genes

415 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
fimbrial biogenesis outer membrane usher proteinD9E35_15940Not AvailableNegative3379179 - 338183096649.2
fimbrial chaperone protein fimcD9E35_15945Not AvailableNegative3381872 - 338258226107.7
fimbrial proteinD9E35_15950Not AvailableNegative3382943 - 338350619145.6
type ii toxin-antitoxin system hipa family toxinD9E35_15965Not AvailableNegative3384480 - 338580249337.8
transcriptional regulatorD9E35_15970Not AvailableNegative3385802 - 338606810033.9
autotransporter outer membrane beta-barrel domain-containing proteinD9E35_15975Not AvailableNegative3386279 - 338767950486.6
autoinducer-2 kinaseD9E35_15985Not AvailableNegative3392230 - 339382257648.2
lsrr family transcriptional regulatorD9E35_15990Not AvailableNegative3393901 - 339485433828.0
autoinducer 2 abc transporter atp-binding protein lsraD9E35_15995Not AvailablePositive3395103 - 339663855847.7
autoinducer 2 abc transporter permease lsrcD9E35_16000Not AvailablePositive3396632 - 339766036431.1

Displaying genes 3371 – 3380 of 5190 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total