Escherichia coli strain CVM N17EC1228

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain CVM N17EC1228 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism and possesses flagella, allowing for mobility. It typically exists in pairs or singles and has a mesophilic temperature range, with an optimal growth temperature of 37°C. This strain is host-associated and can thrive in various environments, demonstrating a free-living biotic relationship with a wide array of hosts, including Homo sapiens, Gallus gallus, Bos taurus, and several other mammals, birds, and even plants like Solanum lycopersicum and Brassica oleracea var. italica. CVM N17EC1228 is notable for its pathogenicity in humans, being associated with a range of health effects such as urinary tract infections (UTIs), gastrointestinal infections, and severe conditions like hemorrhagic colitis and hemolytic uremic syndrome (HUS). The strain's ability to cause diverse health issues underscores its clinical significance and public health concern. Collectively, the extensive list of potential hosts and the variety of health effects indicate that E. coli strain CVM N17EC1228 plays a crucial role in both human health and disease ecology. The strain's adaptability to various hosts and environments suggests its potential for transmission across species, emphasizing the importance of monitoring its prevalence to prevent outbreaks of associated infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain CVM N17EC1228

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain CVM N17EC1228
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain CVM N17EC1228

Gene Summary

Adenine Count

1328414 bp

Thymine Count

1313561 bp

Guanine Count

1338976 bp

Cytosine Count

1354881 bp

Genome Length

5346416 bp

Protein-coding Genes

4828 genes

Non-Coding Genes

457 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinD9J11_19990Not AvailableNegative4075860 - 40759854757.28
uric acid transporter uactD9J11_19995Not AvailableNegative4075987 - 407743551761.4
small toxic protein ibsbD9J11_20000Not AvailableNegative4077771 - 40778272063.86
multidrug efflux rnd transporter subunit mdtaD9J11_20005Not AvailablePositive4078106 - 407935344466.8
multidrug efflux rnd transporter permease subunit mdtbD9J11_20010Not AvailablePositive4079353 - 4082475112114.0
multidrug resistance protein mdtcD9J11_20015Not AvailablePositive4082476 - 4085553111035.0
mfs transporterD9J11_20020Not AvailablePositive4085554 - 408696950904.2
two-component sensor histidine kinaseD9J11_20025Not AvailablePositive4086966 - 408836951994.4
two-component system response regulator baerD9J11_20030Not AvailablePositive4088366 - 408908827688.6
duf1508 domain-containing proteinD9J11_20035Not AvailablePositive4089279 - 408961111994.9

Displaying genes 4181 – 4190 of 5295 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total