Escherichia coli strain CVM N17EC0994

Escherichia coli strain CVM N17EC0994 is a Gram-negative bacterium characterized by its rod shape and mobility, facilitated by the presence of flagella. It is a facultative anaerobe, thriving optimally at 37°C within a mesophilic temperature range. This strain is notable for its habitat, primarily associated with various hosts, including Homo sapiens, Gallus gallus, Bos taurus, and numerous other vertebrates and invertebrates. CVM N17EC0994 exhibits a free-living biotic relationship and has a unique genomic structure with a single replicon and a double membrane. The strain has been implicated in a wide array of health effects, particularly in humans, including urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). It is associated with both foodborne and enteric diseases, indicating its potential role as a pathogen in various clinical and environmental contexts. The diversity of hosts suggests that CVM N17EC0994 may play a significant ecological role, contributing to the health of both its animal hosts and the environment. Its ability to cause infections in multiple species highlights its adaptability and potential impact on public health. Understanding the pathogenic mechanisms of this strain can inform strategies to mitigate its health risks, particularly in food safety and infection control.