Escherichia coli strain PNUSAE019399

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain PNUSAE019399 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and mobility, facilitated by the presence of flagella. This strain thrives optimally at 37°C and falls within the mesophilic temperature range. The organism exists in pairs or singles and possesses a single replicon and two membranes, reflecting its typical cellular structure. E. coli PNUSAE019399 is primarily host-associated, having a broad range of potential hosts, including humans (Homo sapiens), domesticated animals such as cattle (Bos taurus) and poultry (Gallus gallus), as well as various other vertebrates and invertebrates, including plants like Solanum lycopersicum and Brassica oleracea var. italica. This diverse host range indicates a versatile ecological niche and the potential for significant biotic interactions. The strain is known for its pathogenicity in humans, contributing to a variety of health issues such as urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions like neonatal meningitis and hemolytic uremic syndrome (HUS). These health effects highlight the strain's role in clinical settings, particularly concerning foodborne infections and nosocomial diseases. The significant number of health effects associated with E. coli PNUSAE019399 underscores its public health impact and the importance of monitoring and understanding its ecological roles within both human and animal populations. The strain's free-living nature, alongside its pathogenic potential, emphasizes the complex dynamics between microbial organisms and their hosts in various environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain PNUSAE019399

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain PNUSAE019399
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain PNUSAE019399

Gene Summary

Adenine Count

1396240 bp

Thymine Count

1379401 bp

Guanine Count

1401953 bp

Cytosine Count

1433963 bp

Genome Length

5630312 bp

Protein-coding Genes

5184 genes

Non-Coding Genes

447 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
oligopeptidase bED600_RS20920Not AvailableNegative4260495 - 426255579434.6
tellurite resistance terb family proteinED600_RS20925Not AvailableNegative4262764 - 426342323776.2
protein yebfED600_RS20930Not AvailableNegative4263750 - 426410612904.3
dna damage-inducible protein yebgED600_RS20935Not AvailableNegative4264173 - 426446310717.5
formate-dependent phosphoribosylglycinamide formyltransferaseED600_RS20940Not AvailablePositive4264597 - 426577542274.2
bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolaseED600_RS20945Not AvailableNegative4265831 - 426647222285.3
phosphogluconate dehydrataseED600_RS20950Not AvailableNegative4266509 - 426832064642.9
glucose-6-phosphate dehydrogenaseED600_RS20955Not AvailableNegative4268555 - 427003055707.5
murr/rpir family transcriptional regulatorED600_RS20960Not AvailablePositive4270368 - 427123731959.3
pyruvate kinase iiED600_RS20965Not AvailablePositive4271365 - 427280751360.3

Displaying genes 4251 – 4260 of 5636 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total