Escherichia coli strain FDAARGOS_539

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FDAARGOS_539 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic growth pattern, allowing it to thrive in both aerobic and anaerobic environments. This strain is motile and possesses flagella, which contributes to its mobility. It is a mesophilic organism, with an optimal growth temperature of 37°C. The strain is typically found in host-associated habitats. FDAARGOS_539 is notable for its wide range of hosts, which includes various species such as Homo sapiens, Gallus gallus, Bos taurus, and Canis lupus familiaris, among others. This diversity indicates its adaptability and potential for transmission across different species, including mammals and birds. In terms of health effects, this strain is associated with numerous pathogenic conditions in humans, such as urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. Other health impacts include diarrhea, pyogenic liver abscesses, and conditions leading to renal failure. The strain's pathogenicity primarily affects humans, highlighting its significance in clinical microbiology and public health. The varied host range and the ability to cause significant health issues suggest that E. coli strain FDAARGOS_539 plays a crucial role in the ecology of microbial infections, particularly in environments where humans and animals interact. Its presence raises concerns about foodborne infections and zoonotic diseases, emphasizing the importance of monitoring such strains for public health implications.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FDAARGOS_539

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FDAARGOS_539
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FDAARGOS_539

Gene Summary

Adenine Count

1317960 bp

Thymine Count

1314735 bp

Guanine Count

1357469 bp

Cytosine Count

1360213 bp

Genome Length

5350663 bp

Protein-coding Genes

4723 genes

Non-Coding Genes

534 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Dna binding proteinEGT48_00150Not AvailableNegative20795 - 2275371481.8
duf905 domain-containing proteinEGT48_00155Not AvailableNegative22812 - 230459208.91
Single-stranded dna-binding proteinEGT48_00160Not AvailableNegative23101 - 2362819424.9
single-stranded dna-binding proteinEGT48_00165Not AvailableNegative23654 - 237944933.94
hypothetical proteinEGT48_00170Not AvailablePositive23693 - 239268830.89
hypothetical proteinEGT48_00175Not AvailableNegative23856 - 240476643.34
hypothetical proteinEGT48_00180Not AvailablePositive23970 - 241948057.55
hypothetical proteinEGT48_00185Not AvailableNegative24098 - 243408074.87
hypothetical proteinEGT48_00190Not AvailableNegative24268 - 244928331.67
Hypothetical proteinEGT48_00195Not AvailableNegative24492 - 2505521184.8

Displaying genes 21 – 30 of 5272 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total