Streptococcus mitis strain BCC22

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mitis strain BCC22 is a Gram-positive bacterium characterized by its cocci shape and arrangement in chains or pairs. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It is mesophilic, meaning it prefers moderate temperature conditions for optimal growth. Notably, Streptococcus mitis BCC22 possesses a single membrane and one replicon, indicating a relatively simple cellular structure. This strain is non-motile and does not possess flagella, suggesting that its movement is influenced by environmental factors rather than active locomotion. Streptococcus mitis is commonly found associated with humans, particularly as part of the normal flora in the mouth and upper respiratory tract. However, it can also be implicated in several health conditions, including endocarditis, peritonitis, invasive streptococcal disease, and S. mitis meningitis. As a free-living bacterium, S. mitis BCC22 demonstrates the complex interplay between commensal organisms and host health. While it can contribute to normal microbiota, its potential to cause invasive diseases highlights the importance of maintaining microbial balance within the host. The presence of this strain in clinical settings underscores the relevance of understanding its pathogenic capabilities, particularly regarding its role in human health and disease dynamics.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mitis
Strainstrain BCC22

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mitis strain BCC22
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mitis strain BCC22 D8788_contig052, whole genome

Gene Summary

Adenine Count

598467 bp

Thymine Count

611439 bp

Guanine Count

393031 bp

Cytosine Count

411623 bp

Genome Length

2018256 bp

Protein-coding Genes

1849 genes

Non-Coding Genes

112 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lipopolysaccharide export system atp-binding protein lptbD8788_02595Not AvailableNegative525972 - 52673628235.4
high-affinity branched-chain amino acid transport system permease protein livhD8788_02600Not AvailableNegative526736 - 52769233550.3
high-affinity branched-chain amino acid transport system permease protein livhD8788_02605Not AvailableNegative527696 - 52856530870.3
leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein precursorD8788_02610Not AvailableNegative528681 - 52984140378.4
hypothetical proteinD8788_02615Not AvailableNegative529908 - 53019511464.9
atp-dependent clp protease proteolytic subunitD8788_02620Not AvailableNegative530274 - 53086421341.6
uracil phosphoribosyltransferaseD8788_02625Not AvailableNegative531040 - 53166922873.1
riboflavin biosynthesis protein ribdD8788_02630Not AvailableNegative531758 - 53222517396.0
hth-type transcriptional regulator ethrD8788_02635Not AvailableNegative532244 - 53280121813.6
fatty acid-binding proteinD8788_02640Not AvailablePositive532926 - 53377130723.8

Displaying genes 521 – 530 of 1957 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Invasive streptococcal diseaseCausesPMC9328907
EndocarditisCausesPMC2828477
S. mitis meningitisCausesPMC2828477
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total