Streptococcus mitis strain BCC22

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mitis strain BCC22 is a Gram-positive bacterium characterized by its cocci shape and arrangement in chains or pairs. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It is mesophilic, meaning it prefers moderate temperature conditions for optimal growth. Notably, Streptococcus mitis BCC22 possesses a single membrane and one replicon, indicating a relatively simple cellular structure. This strain is non-motile and does not possess flagella, suggesting that its movement is influenced by environmental factors rather than active locomotion. Streptococcus mitis is commonly found associated with humans, particularly as part of the normal flora in the mouth and upper respiratory tract. However, it can also be implicated in several health conditions, including endocarditis, peritonitis, invasive streptococcal disease, and S. mitis meningitis. As a free-living bacterium, S. mitis BCC22 demonstrates the complex interplay between commensal organisms and host health. While it can contribute to normal microbiota, its potential to cause invasive diseases highlights the importance of maintaining microbial balance within the host. The presence of this strain in clinical settings underscores the relevance of understanding its pathogenic capabilities, particularly regarding its role in human health and disease dynamics.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mitis
Strainstrain BCC22

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mitis strain BCC22
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mitis strain BCC22 D8788_contig052, whole genome

Gene Summary

Adenine Count

598467 bp

Thymine Count

611439 bp

Guanine Count

393031 bp

Cytosine Count

411623 bp

Genome Length

2018256 bp

Protein-coding Genes

1849 genes

Non-Coding Genes

112 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
6-phosphogluconolactonaseD8788_06435Not AvailablePositive1322604 - 132361737785.8
elongation factor tuD8788_06440Not AvailableNegative1323898 - 132509443987.4
ai-2 transport protein tqsaD8788_06445Not AvailableNegative1325301 - 132641041460.8
d-alanyl-d-alanine carboxypeptidase daca precursorD8788_06450Not AvailablePositive1326513 - 132775445077.6
thiol-disulfide oxidoreductase resaD8788_06455Not AvailableNegative1327944 - 132851021174.5
thiol:disulfide interchange protein dsbd precursorD8788_06460Not AvailableNegative1328522 - 132922925874.7
atp synthase epsilon chainD8788_06465Not AvailableNegative1329426 - 132984515543.6
atp synthase subunit betaD8788_06470Not AvailableNegative1329856 - 133126250911.1
atp synthase gamma chainD8788_06475Not AvailableNegative1331348 - 133222632325.7
atp synthase subunit alphaD8788_06480Not AvailableNegative1332242 - 133374754575.5

Displaying genes 1291 – 1300 of 1957 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Invasive streptococcal diseaseCausesPMC9328907
EndocarditisCausesPMC2828477
S. mitis meningitisCausesPMC2828477
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total