Streptococcus intermedius strain A2

Gram-positiveCocciFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus intermedius strain A2 is a Gram-positive, facultative anaerobic cocci that is primarily found in the oral cavity, including dental plaques and the mouth. Its cell arrangement typically appears in pairs or chains. This strain possesses a single replicon and is characterized by the presence of flagella. This microorganism is associated with a variety of health effects, particularly in humans (Homo sapiens) and rabbits (Oryctolagus cuniculus). It can lead to serious conditions such as bacteremia, brain abscesses, and infective endocarditis, among others. Other significant health impacts include liver abscesses, osteomyelitis, periodontitis, and intracranial suppuration. The strain is known to be involved in deep infections, including deep neck infections and cervical lymphadenitis, indicating its potential for invasive pathogenicity. Streptococcus intermedius strain A2’s ability to thrive in both aerobic and anaerobic environments allows it to inhabit diverse niches within the host, particularly in the oral cavity where it can contribute to dental diseases. Its pathogenic potential is underscored by its capacity to cause various abscesses and systemic infections. The strain's presence in brain abscesses suggests a specific ecological role in human health, particularly in conditions where the normal barrier to infection is compromised. Understanding its behavior and effects in these habitats may provide insights into managing infections associated with this organism.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus intermedius
Strainstrain A2

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus intermedius strain A2
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbrain abscesses; dental plaques; mouth; oral cavity
Biotic relationshipNot Available
Host(s)Homo sapiens, Oryctolagus cuniculus
Cell arrangementPairs, Chains
SporulationNot Available
Energy sourceNot Available
PathogenicityAnimal

Genome Summary

Streptococcus intermedius strain A2 D8829_contig026, whole genome

Gene Summary

Adenine Count

623573 bp

Thymine Count

625202 bp

Guanine Count

390311 bp

Cytosine Count

362655 bp

Genome Length

2003686 bp

Protein-coding Genes

1926 genes

Non-Coding Genes

98 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
putative nad(p)h nitroreductaseD8829_01940Not AvailablePositive395133 - 39573822863.4
beta-ala-xaa dipeptidaseD8829_01945Not AvailablePositive395767 - 39716751274.5
multidrug resistance-like atp-binding protein mdlbD8829_01950Not AvailablePositive398014 - 39962461739.7
uracil dna glycosylase superfamily proteinD8829_01955Not AvailablePositive400269 - 40085322715.2
transcriptional regulator slyaD8829_01960Not AvailablePositive400956 - 40140817663.5
glycine betaine/carnitine/choline-binding protein opucc precursorD8829_01965Not AvailablePositive401405 - 40293756051.2
putative osmoprotectant uptake system atp-binding protein yehxD8829_01970Not AvailablePositive402934 - 40365326448.2
hypothetical proteinD8829_01975Not AvailablePositive404255 - 40615072899.0
glycosyl hydrolases family 25D8829_01980Not AvailableNegative406585 - 40742431591.4
lipid ii flippase ftswD8829_01985Not AvailablePositive407720 - 40895245092.4

Displaying genes 441 – 450 of 2028 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PeriodontitisCausesPMC11792871
Pyogenic infection of the central nervous system, pleural space or liverCausesPMC11792871
Intracranial suppurationCausesPMC11792871
BacteraemiaCausesPMC11792871
IcsCausesPMC11792871
Invasive infectionCausesPMC11792871
Brain abscessesCausesPMC11792871
Deep infectionsCausesPMC1435756
Deep neck infectionsCausesPMC1435756
Cervical lymphadenitisCausesPMC1435756

Displaying health effects 1 – 10 of 27 in total