Streptococcus mitis strain BCC49

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mitis strain BCC49 is a Gram-positive, cocci-shaped bacterium that typically exists in chains or pairs. This strain is classified as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments. It is non-motile and does not possess flagella, which aligns with its characteristic cell arrangement. S. mitis strain BCC49 is mesophilic, meaning it prefers moderate temperature ranges for optimal growth. This bacterium is primarily associated with Homo sapiens, where it plays a complex role in human health. While it can be a free-living organism, S. mitis strain BCC49 is also implicated in various health conditions, including endocarditis, peritonitis, invasive streptococcal disease, and S. mitis meningitis. The strain's ability to cause these serious infections highlights its pathogenic potential despite its presence as a commensal organism in the human microbiome. With a single replicon and one membrane, S. mitis strain BCC49 does not undergo sporulation, which may affect its survival strategies in varying environments. Understanding its biotic relationships and pathogenicity offers insights into the dynamics of microbial communities in human hosts and the potential risks posed by opportunistic pathogens like S. mitis. Continued study of such strains is essential to grasp their ecological roles and impacts on human health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mitis
Strainstrain BCC49

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mitis strain BCC49
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mitis strain BCC49 D8843_contig066, whole genome

Gene Summary

Adenine Count

616991 bp

Thymine Count

603197 bp

Guanine Count

416908 bp

Cytosine Count

392766 bp

Genome Length

2034557 bp

Protein-coding Genes

1788 genes

Non-Coding Genes

156 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
n-acetylmuramoyl-l-alanine amidase domain-containing protein precursorD8843_01805Not AvailablePositive364829 - 36593240375.0
hypothetical proteinD8843_01810Not AvailablePositive365953 - 36684631916.7
hypothetical proteinD8843_01815Not AvailablePositive366857 - 36768432197.7
hypothetical proteinD8843_01820Not AvailablePositive367750 - 36831921474.7
hypothetical proteinD8843_01825Not AvailablePositive368489 - 36882413155.0
tyrosine recombinase xercD8843_01830Not AvailablePositive368862 - 37000144481.4
hypothetical proteinD8843_01835Not AvailablePositive370583 - 37151233955.8
ferredoxin--nad(p)(+) reductase (naphthalene dioxygenase/salicylate 5-hydroxylase ferredoxin-specific)D8843_02145Not AvailableNegative414009 - 41519945708.1
putative glutamine abc transporter permease protein glnpD8843_02150Not AvailableNegative415343 - 41600224411.6
putative glutamine abc transporter permease protein glnmD8843_02155Not AvailableNegative416012 - 41668925032.1

Displaying genes 481 – 490 of 1944 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Invasive streptococcal diseaseCausesPMC9328907
EndocarditisCausesPMC2828477
S. mitis meningitisCausesPMC2828477
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total