Streptococcus mitis strain BCC49

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mitis strain BCC49 is a Gram-positive, cocci-shaped bacterium that typically exists in chains or pairs. This strain is classified as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments. It is non-motile and does not possess flagella, which aligns with its characteristic cell arrangement. S. mitis strain BCC49 is mesophilic, meaning it prefers moderate temperature ranges for optimal growth. This bacterium is primarily associated with Homo sapiens, where it plays a complex role in human health. While it can be a free-living organism, S. mitis strain BCC49 is also implicated in various health conditions, including endocarditis, peritonitis, invasive streptococcal disease, and S. mitis meningitis. The strain's ability to cause these serious infections highlights its pathogenic potential despite its presence as a commensal organism in the human microbiome. With a single replicon and one membrane, S. mitis strain BCC49 does not undergo sporulation, which may affect its survival strategies in varying environments. Understanding its biotic relationships and pathogenicity offers insights into the dynamics of microbial communities in human hosts and the potential risks posed by opportunistic pathogens like S. mitis. Continued study of such strains is essential to grasp their ecological roles and impacts on human health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mitis
Strainstrain BCC49

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mitis strain BCC49
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mitis strain BCC49 D8843_contig066, whole genome

Gene Summary

Adenine Count

616991 bp

Thymine Count

603197 bp

Guanine Count

416908 bp

Cytosine Count

392766 bp

Genome Length

2034557 bp

Protein-coding Genes

1788 genes

Non-Coding Genes

156 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
methylated-dna--protein-cysteine methyltransferaseD8843_01405Not AvailablePositive292399 - 29290818749.6
regulatory protein mgsrD8843_01410Not AvailablePositive292921 - 29327713298.2
putative amino-acid permease protein yxenD8843_01415Not AvailablePositive293435 - 29423528962.9
l-cystine import atp-binding protein tcynD8843_01420Not AvailablePositive294235 - 29497827442.1
hypothetical proteinD8843_01425Not AvailablePositive295056 - 2952808258.8
thioredoxin reductaseD8843_01430Not AvailablePositive295346 - 29625733091.1
putative trmh family trna/rrna methyltransferaseD8843_01435Not AvailableNegative296297 - 29702526371.9
peptide deformylaseD8843_01440Not AvailableNegative297070 - 29768122662.4
capsule biosynthesis protein capaD8843_01445Not AvailablePositive297856 - 29918150436.8
sugar phosphatase ybivD8843_01450Not AvailablePositive299203 - 30003030880.2

Displaying genes 401 – 410 of 1944 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Invasive streptococcal diseaseCausesPMC9328907
EndocarditisCausesPMC2828477
S. mitis meningitisCausesPMC2828477
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total