Streptococcus oralis strain BCA21

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus oralis strain BCA21 is a Gram-positive, facultative anaerobic bacterium characterized by its cocci shape and arrangement in pairs and chains. It is part of the normal microbiota found in the human host, particularly associated with Homo sapiens. The strain has been identified as a free-living organism, which contributes to its capacity to inhabit various ecological niches within the human body. This strain is mesophilic, indicating that it thrives in moderate temperature conditions, which aligns with the typical human body temperature. Notably, Streptococcus oralis BCA21 does not exhibit mobility and lacks flagella, which influences its ecological interactions and colonization strategies. Streptococcus oralis strain BCA21 is recognized for its pathogenic potential, being implicated in several serious health conditions, including endocarditis, peritonitis, meningitis, and invasive diseases. Its role in infective endocarditis highlights its capability to enter normally sterile sites, leading to significant health implications. The presence of a single replicon suggests a streamlined genomic organization, which may be advantageous for its survival and adaptation within host environments. Understanding the traits and pathogenicity of Streptococcus oralis strain BCA21 contributes to the broader knowledge of human-associated microbiota and their potential to cause disease, emphasizing the importance of maintaining microbial balance within the human body to prevent opportunistic infections.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus oralis
Strainstrain BCA21

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus oralis strain BCA21
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Ovis aries
Cell arrangementPairs - Chains
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus oralis strain BCA21 D8864_contig020, whole genome

Gene Summary

Adenine Count

567437 bp

Thymine Count

579379 bp

Guanine Count

388482 bp

Cytosine Count

416749 bp

Genome Length

1953432 bp

Protein-coding Genes

1790 genes

Non-Coding Genes

101 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sensor histidine kinase grasD8864_03595Not AvailableNegative734491 - 73546537846.8
response regulator protein grarD8864_03600Not AvailableNegative735458 - 73613525879.6
fatty acid metabolism regulator proteinD8864_03605Not AvailablePositive736463 - 73702621592.7
hypothetical proteinD8864_03610Not AvailablePositive737112 - 73788828719.2
lipase (class 3)D8864_03615Not AvailablePositive738000 - 73907341119.0
phenoxybenzoate dioxygenase subunit betaD8864_03620Not AvailablePositive739236 - 74042945438.1
putative metallo-hydrolaseD8864_03625Not AvailablePositive740531 - 74116023690.0
neutral endopeptidaseD8864_03630Not AvailableNegative741199 - 74309171767.2
high-affinity zinc uptake system atp-binding protein znucD8864_03635Not AvailablePositive743270 - 74399226784.7
manganese transport system membrane protein mntbD8864_03640Not AvailablePositive743989 - 74483730199.3

Displaying genes 771 – 780 of 1878 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC6849159
Infective endocarditisCausesPMC6849159
Invasive diseaseCausesPMC9328907
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total