Streptococcus oralis strain BCA21

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus oralis strain BCA21 is a Gram-positive, facultative anaerobic bacterium characterized by its cocci shape and arrangement in pairs and chains. It is part of the normal microbiota found in the human host, particularly associated with Homo sapiens. The strain has been identified as a free-living organism, which contributes to its capacity to inhabit various ecological niches within the human body. This strain is mesophilic, indicating that it thrives in moderate temperature conditions, which aligns with the typical human body temperature. Notably, Streptococcus oralis BCA21 does not exhibit mobility and lacks flagella, which influences its ecological interactions and colonization strategies. Streptococcus oralis strain BCA21 is recognized for its pathogenic potential, being implicated in several serious health conditions, including endocarditis, peritonitis, meningitis, and invasive diseases. Its role in infective endocarditis highlights its capability to enter normally sterile sites, leading to significant health implications. The presence of a single replicon suggests a streamlined genomic organization, which may be advantageous for its survival and adaptation within host environments. Understanding the traits and pathogenicity of Streptococcus oralis strain BCA21 contributes to the broader knowledge of human-associated microbiota and their potential to cause disease, emphasizing the importance of maintaining microbial balance within the human body to prevent opportunistic infections.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus oralis
Strainstrain BCA21

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus oralis strain BCA21
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Ovis aries
Cell arrangementPairs - Chains
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus oralis strain BCA21 D8864_contig020, whole genome

Gene Summary

Adenine Count

567437 bp

Thymine Count

579379 bp

Guanine Count

388482 bp

Cytosine Count

416749 bp

Genome Length

1953432 bp

Protein-coding Genes

1790 genes

Non-Coding Genes

101 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinD8864_01245Not AvailablePositive254518 - 25527329404.6
uracil-dna glycosylaseD8864_01250Not AvailablePositive255285 - 25593823951.8
8-oxo-dgtp diphosphataseD8864_01255Not AvailablePositive255948 - 25641217783.0
dihydroorotaseD8864_01260Not AvailablePositive256425 - 25769345244.1
multidrug resistance protein normD8864_01265Not AvailablePositive257735 - 25907549345.4
acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alphaD8864_01270Not AvailablePositive259254 - 26022235104.1
2-oxoisovalerate dehydrogenase subunit betaD8864_01275Not AvailablePositive260239 - 26123135851.2
dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complexD8864_01280Not AvailablePositive261340 - 26238338041.6
dihydrolipoyl dehydrogenaseD8864_01285Not AvailablePositive262429 - 26413260195.1
lipoate-protein ligase lpljD8864_01290Not AvailablePositive264328 - 26531737724.9

Displaying genes 301 – 310 of 1878 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC6849159
Infective endocarditisCausesPMC6849159
Invasive diseaseCausesPMC9328907
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total