Streptococcus mitis strain BCC15

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mitis strain BCC15 is a Gram-positive, cocci-shaped bacterium known for its presence in host-associated habitats, specifically in Homo sapiens. This organism typically arranges itself in chains or pairs and is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. S. mitis strain BCC15 does not exhibit mobility and does not possess flagella. This strain is mesophilic, indicating that it grows optimally at moderate temperatures. It contains one replicon and has a single membrane structure. As a free-living bacterium, S. mitis strain BCC15 engages in various biotic relationships within its human host. Clinically, S. mitis strain BCC15 is significant due to its association with several health conditions. It is implicated in endocarditis, peritonitis, invasive streptococcal disease, and S. mitis meningitis, illustrating its potential pathogenicity. The absence of sporulation suggests that it relies on other survival strategies to endure adverse conditions. The understanding of S. mitis strain BCC15's traits underscores its role in human health. Its ability to cause serious infections highlights the importance of studying its ecological niche within the human microbiome and the implications for infectious disease management. The strain's characteristics serve as a reminder of the complex interactions between commensal and pathogenic bacteria in human hosts.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mitis
Strainstrain BCC15

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mitis strain BCC15
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mitis strain BCC15 D8865_contig044, whole genome

Gene Summary

Adenine Count

679617 bp

Thymine Count

674109 bp

Guanine Count

456391 bp

Cytosine Count

429206 bp

Genome Length

2242568 bp

Protein-coding Genes

2044 genes

Non-Coding Genes

142 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinD8865_09610Not AvailableNegative1972171 - 197260516904.7
hypothetical proteinD8865_09615Not AvailableNegative1972609 - 197293811894.3
esx-1 secretion system protein eccca1D8865_09620Not AvailableNegative1972950 - 1977326166843.0
putative membrane protein essbD8865_09625Not AvailableNegative1977336 - 197849043970.7
yukdD8865_09630Not AvailableNegative1978505 - 19787478846.9
firmicute esat-6 protein secretion system essaD8865_09635Not AvailableNegative1978871 - 197933217726.6
hypothetical proteinD8865_09640Not AvailableNegative1979334 - 1982573119722.0
virulence factor esxaD8865_09645Not AvailableNegative1982636 - 198293211234.1
inosine 5'-monophosphate dehydrogenaseD8865_09650Not AvailableNegative1983245 - 198390124205.3
high-affinity branched-chain amino acid transport atp-binding protein livfD8865_09655Not AvailableNegative1984213 - 19844949982.35

Displaying genes 1931 – 1940 of 2183 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Invasive streptococcal diseaseCausesPMC9328907
EndocarditisCausesPMC2828477
S. mitis meningitisCausesPMC2828477
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total