Streptococcus oralis strain BCA18

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus oralis strain BCA18 is a Gram-positive bacterium that exhibits a cocci shape and typically arranges itself in pairs or chains. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments, which contributes to its adaptability within host-associated habitats, particularly in humans (Homo sapiens). As a non-motile organism, S. oralis BCA18 does not possess flagella, yet it remains capable of establishing and maintaining a presence in the human body. The strain is mesophilic, indicating that it thrives at moderate temperatures, which is consistent with the conditions found in human tissues. The bacterium has a single replicon, reflecting a relatively simple genomic organization. S. oralis BCA18 is known to have significant health implications, being associated with various serious infections, including endocarditis, peritonitis, meningitis, and invasive diseases such as infective endocarditis. Its pathogenicity is notably directed towards humans, underscoring its role as a potential opportunistic pathogen, particularly in immunocompromised individuals. In terms of ecological insight, S. oralis BCA18's free-living biotic relationship suggests that while it can exist independently, it is also an integral part of the human microbiome. This duality may influence its pathogenic potential, as disruptions in the microbial balance can lead to opportunistic infections. Understanding the traits of this strain provides essential information for assessing its role in human health and disease.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus oralis
Strainstrain BCA18

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus oralis strain BCA18
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Ovis aries
Cell arrangementPairs - Chains
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus oralis strain BCA18 D8894_contig041, whole genome

Gene Summary

Adenine Count

581845 bp

Thymine Count

588748 bp

Guanine Count

394135 bp

Cytosine Count

424934 bp

Genome Length

1992542 bp

Protein-coding Genes

1838 genes

Non-Coding Genes

107 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
chromosomal replication initiator protein dnaaD8894_09470Not AvailableNegative1927838 - 192919951828.1
chromosome-partitioning protein spo0jD8894_09475Not AvailableNegative1929416 - 193015928450.5
serine protease do-like htraD8894_09480Not AvailableNegative1930232 - 193142841989.1
putative dna-directed rna polymerase subunit deltaD8894_09485Not AvailablePositive1932035 - 193264022853.3
ctp synthaseD8894_09490Not AvailablePositive1932972 - 193457959237.1
hypothetical proteinD8894_09495Not AvailablePositive1934675 - 193497411168.5
thioredoxin-like protein ytppD8894_09500Not AvailablePositive1934971 - 193528812236.6
phenylalanine--trna ligase beta subunitD8894_09505Not AvailablePositive1935303 - 193592922877.6
nadp-dependent 3-hydroxy acid dehydrogenase ydfgD8894_09510Not AvailablePositive1935971 - 193673227606.3
single-stranded dna-binding protein ssbD8894_09515Not AvailablePositive1936810 - 193720514834.6

Displaying genes 1901 – 1910 of 1934 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC6849159
Infective endocarditisCausesPMC6849159
Invasive diseaseCausesPMC9328907
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total