Streptococcus oralis strain BCA18

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus oralis strain BCA18 is a Gram-positive bacterium that exhibits a cocci shape and typically arranges itself in pairs or chains. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments, which contributes to its adaptability within host-associated habitats, particularly in humans (Homo sapiens). As a non-motile organism, S. oralis BCA18 does not possess flagella, yet it remains capable of establishing and maintaining a presence in the human body. The strain is mesophilic, indicating that it thrives at moderate temperatures, which is consistent with the conditions found in human tissues. The bacterium has a single replicon, reflecting a relatively simple genomic organization. S. oralis BCA18 is known to have significant health implications, being associated with various serious infections, including endocarditis, peritonitis, meningitis, and invasive diseases such as infective endocarditis. Its pathogenicity is notably directed towards humans, underscoring its role as a potential opportunistic pathogen, particularly in immunocompromised individuals. In terms of ecological insight, S. oralis BCA18's free-living biotic relationship suggests that while it can exist independently, it is also an integral part of the human microbiome. This duality may influence its pathogenic potential, as disruptions in the microbial balance can lead to opportunistic infections. Understanding the traits of this strain provides essential information for assessing its role in human health and disease.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus oralis
Strainstrain BCA18

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus oralis strain BCA18
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Ovis aries
Cell arrangementPairs - Chains
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus oralis strain BCA18 D8894_contig041, whole genome

Gene Summary

Adenine Count

581845 bp

Thymine Count

588748 bp

Guanine Count

394135 bp

Cytosine Count

424934 bp

Genome Length

1992542 bp

Protein-coding Genes

1838 genes

Non-Coding Genes

107 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctional oligoribonuclease and pap phosphatase nrnaD8894_06030Not AvailableNegative1240603 - 124257673270.5
nitronate monooxygenaseD8894_06035Not AvailableNegative1242752 - 124369033010.4
putative quorum-quenching lactonase ytnpD8894_06040Not AvailableNegative1243797 - 124471435553.4
acyl-coa dehydrogenaseD8894_06045Not AvailableNegative1244718 - 124583041680.3
hth-type transcriptional regulator cynrD8894_06050Not AvailableNegative1245846 - 124673934566.3
acetate coa-transferase subunit betaD8894_06055Not AvailableNegative1246949 - 124760222713.6
butyrate--acetoacetate coa-transferase subunit aD8894_06060Not AvailableNegative1247604 - 124832625832.1
putative enoyl-coa hydratase echa8D8894_06065Not AvailableNegative1248342 - 124912128176.4
acetyl-coa acetyltransferaseD8894_06070Not AvailableNegative1249442 - 125062041012.6
putative 3-hydroxybutyryl-coa dehydrogenaseD8894_06075Not AvailableNegative1250639 - 125148430752.6

Displaying genes 1211 – 1220 of 1934 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC6849159
Infective endocarditisCausesPMC6849159
Invasive diseaseCausesPMC9328907
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total