Streptococcus oralis strain BCA18

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus oralis strain BCA18 is a Gram-positive bacterium that exhibits a cocci shape and typically arranges itself in pairs or chains. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments, which contributes to its adaptability within host-associated habitats, particularly in humans (Homo sapiens). As a non-motile organism, S. oralis BCA18 does not possess flagella, yet it remains capable of establishing and maintaining a presence in the human body. The strain is mesophilic, indicating that it thrives at moderate temperatures, which is consistent with the conditions found in human tissues. The bacterium has a single replicon, reflecting a relatively simple genomic organization. S. oralis BCA18 is known to have significant health implications, being associated with various serious infections, including endocarditis, peritonitis, meningitis, and invasive diseases such as infective endocarditis. Its pathogenicity is notably directed towards humans, underscoring its role as a potential opportunistic pathogen, particularly in immunocompromised individuals. In terms of ecological insight, S. oralis BCA18's free-living biotic relationship suggests that while it can exist independently, it is also an integral part of the human microbiome. This duality may influence its pathogenic potential, as disruptions in the microbial balance can lead to opportunistic infections. Understanding the traits of this strain provides essential information for assessing its role in human health and disease.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus oralis
Strainstrain BCA18

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus oralis strain BCA18
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Ovis aries
Cell arrangementPairs - Chains
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus oralis strain BCA18 D8894_contig041, whole genome

Gene Summary

Adenine Count

581845 bp

Thymine Count

588748 bp

Guanine Count

394135 bp

Cytosine Count

424934 bp

Genome Length

1992542 bp

Protein-coding Genes

1838 genes

Non-Coding Genes

107 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
single-stranded-dna-specific exonuclease recjD8894_00255Not AvailableNegative47695 - 4997184698.4
glutamine transport atp-binding protein glnqD8894_00260Not AvailablePositive50092 - 5085028149.1
major cell-binding factor precursorD8894_00265Not AvailablePositive50861 - 5165529522.3
putative glutamine abc transporter permease protein glnmD8894_00270Not AvailablePositive51668 - 5234525015.2
putative glutamine abc transporter permease protein glnpD8894_00275Not AvailablePositive52355 - 5301424480.6
hypothetical proteinD8894_00280Not AvailablePositive53145 - 5392730533.5
putative hth-type transcriptional regulator ywnaD8894_00285Not AvailableNegative54070 - 5450715712.2
hypothetical proteinD8894_00290Not AvailableNegative54672 - 5561334414.9
phosphodiesteraseD8894_00295Not AvailableNegative55774 - 5662532703.9
hypothetical proteinD8894_00300Not AvailablePositive56821 - 5719515004.0

Displaying genes 111 – 120 of 1934 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC6849159
Infective endocarditisCausesPMC6849159
Invasive diseaseCausesPMC9328907
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total