Helicobacter pylori strain ZH102 33

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH102 33 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and presence of flagella. It exhibits a single-cell arrangement and is notable for its habitat association with various hosts, including Homo sapiens, Gallus gallus, and other mammals and birds. The strain is mesophilic, with an optimal growth temperature of 37°C. This strain is free-living and possesses a unique biotic relationship with its hosts, contributing to a range of health issues. H. pylori is implicated in chronic gastric inflammation and various forms of gastric cancer, including adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. It is also associated with gastrointestinal diseases such as peptic ulcer disease, chronic gastritis, and functional dyspepsia. The extensive list of health effects indicates a significant pathogenic potential, particularly in humans, where it can provoke severe conditions like gastric ulcers and GERD (gastroesophageal reflux disease). Given its association with serious gastrointestinal diseases, H. pylori strain ZH102 33 serves as a crucial example of how specific bacterial strains can influence host health. The strain's ability to thrive within the gastric environment underscores the complex interactions between pathogens and their hosts, illustrating the need for ongoing research into management and treatment strategies for the diseases associated with H. pylori infections.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain ZH102 33

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain ZH102 33
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH102 33, whole genome shotgun

Gene Summary

Adenine Count

479506 bp

Thymine Count

472135 bp

Guanine Count

311349 bp

Cytosine Count

299924 bp

Genome Length

1565210 bp

Protein-coding Genes

1417 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
trna threonylcarbamoyladenosine biosynthesis protein tsabEC552_01400Not AvailableNegative287795 - 28821716046.2
udp-3-o-[3-hydroxymyristoyl] n-acetylglucosamine deacetylaseEC552_01405Not AvailableNegative288290 - 28917732602.9
septum site-determining protein mincEC552_01410Not AvailableNegative289174 - 28982725215.7
m23 family metallopeptidaseEC552_01415Not AvailableNegative289764 - 29103248295.9
outer membrane beta-barrel proteinEC552_01420Not AvailableNegative291096 - 29203735718.0
outer membrane beta-barrel proteinEC552_01425Not AvailableNegative292049 - 29290332451.4
hypothetical proteinEC552_01430Not AvailableNegative292893 - 29361527365.2
3-methyl-2-oxobutanoate hydroxymethyltransferaseEC552_01435Not AvailablePositive293764 - 29457629878.6
holliday junction branch migration dna helicase ruvbEC552_01440Not AvailablePositive294577 - 29558737265.5
sec-independent protein translocase subunit tatbEC552_01445Not AvailablePositive295655 - 29612217778.1

Displaying genes 271 – 280 of 1459 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total