Helicobacter pylori strain ZH102 33

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH102 33 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and presence of flagella. It exhibits a single-cell arrangement and is notable for its habitat association with various hosts, including Homo sapiens, Gallus gallus, and other mammals and birds. The strain is mesophilic, with an optimal growth temperature of 37°C. This strain is free-living and possesses a unique biotic relationship with its hosts, contributing to a range of health issues. H. pylori is implicated in chronic gastric inflammation and various forms of gastric cancer, including adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. It is also associated with gastrointestinal diseases such as peptic ulcer disease, chronic gastritis, and functional dyspepsia. The extensive list of health effects indicates a significant pathogenic potential, particularly in humans, where it can provoke severe conditions like gastric ulcers and GERD (gastroesophageal reflux disease). Given its association with serious gastrointestinal diseases, H. pylori strain ZH102 33 serves as a crucial example of how specific bacterial strains can influence host health. The strain's ability to thrive within the gastric environment underscores the complex interactions between pathogens and their hosts, illustrating the need for ongoing research into management and treatment strategies for the diseases associated with H. pylori infections.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain ZH102 33

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain ZH102 33
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH102 33, whole genome shotgun

Gene Summary

Adenine Count

479506 bp

Thymine Count

472135 bp

Guanine Count

311349 bp

Cytosine Count

299924 bp

Genome Length

1565210 bp

Protein-coding Genes

1417 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinEC552_01130Not AvailableNegative233193 - 23420339221.1
sura proteinEC552_01135Not AvailableNegative234214 - 23546147748.2
asp-trna(asn)/glu-trna(gln) amidotransferase subunit gatbEC552_01140Not AvailableNegative235461 - 23688853257.2
insulinase family proteinEC552_01145Not AvailableNegative236885 - 23818348817.6
dehypoxanthine futalosine cyclaseEC552_01150Not AvailableNegative238189 - 23934043525.8
outer membrane protein assembly factor bamaEC552_01155Not AvailableNegative239252 - 241972101560.0
aminofutalosine synthase mqneEC552_01160Not AvailableNegative242055 - 24313741339.9
non-heme ferritinEC552_01165Not AvailablePositive243436 - 24393919314.8
phosphoserine phosphatase serbEC552_01170Not AvailablePositive243954 - 24457723033.1
Trna-proNot AvailableNot AvailablePositive245935 - 246012Not Available

Displaying genes 221 – 230 of 1459 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total