Helicobacter pylori strain ZH100 80

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH100 80 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and presence of flagella, which allows for motility despite its designation as non-motile in some contexts. This strain is typically found in a host-associated habitat and exhibits a biotic relationship that is free-living. It has a single replicon and two membranes, which are common features of Gram-negative bacteria. ZH100 80 thrives optimally at 37°C, fitting within the mesophilic temperature range. It has been identified in a variety of hosts, including Homo sapiens, Gallus gallus, and various mammals and birds, indicating a broad ecological niche. The health effects associated with Helicobacter pylori strain ZH100 80 are significant, as it is linked to several gastrointestinal diseases. These include chronic gastric inflammation, gastric ulcers, and various forms of gastric cancer, such as adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. The strain is also implicated in more common conditions like GERD and functional dyspepsia. The pathogenicity of H. pylori strain ZH100 80 in humans underscores its role in chronic health issues, prompting a deeper understanding of its mechanisms and interactions within the gastrointestinal tract. This relationship between H. pylori and its human hosts highlights the importance of studying microbial strains not only for their pathogenic potential but also for their ecological roles in host health and disease dynamics.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain ZH100 80

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain ZH100 80
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH100 80, whole genome shotgun

Gene Summary

Adenine Count

494417 bp

Thymine Count

496721 bp

Guanine Count

318568 bp

Cytosine Count

312565 bp

Genome Length

1627857 bp

Protein-coding Genes

1487 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
flagellar motor switch protein flimEC550_00200Not AvailableNegative39806 - 4087040173.1
rna polymerase sigma factor fliaEC550_00205Not AvailableNegative40863 - 4163029500.4
hypothetical proteinEC550_00210Not AvailableNegative41608 - 4192211966.6
mind/para family proteinEC550_00215Not AvailableNegative41927 - 4281132070.8
flagellar biosynthesis protein flhfEC550_00220Not AvailableNegative42808 - 4418752383.0
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinaseEC550_00225Not AvailableNegative44181 - 4467219255.8
aminopeptidase p family proteinEC550_00230Not AvailableNegative44669 - 4574240852.6
type ii 3-dehydroquinate dehydrataseEC550_00235Not AvailableNegative45756 - 4625918484.4
o-antigen ligase family proteinEC550_00240Not AvailableNegative46388 - 4767749461.9
30s ribosomal protein s15EC550_00245Not AvailableNegative47707 - 4797910390.9

Displaying genes 41 – 50 of 1529 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total