Helicobacter pylori strain ZH100 80

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH100 80 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and presence of flagella, which allows for motility despite its designation as non-motile in some contexts. This strain is typically found in a host-associated habitat and exhibits a biotic relationship that is free-living. It has a single replicon and two membranes, which are common features of Gram-negative bacteria. ZH100 80 thrives optimally at 37°C, fitting within the mesophilic temperature range. It has been identified in a variety of hosts, including Homo sapiens, Gallus gallus, and various mammals and birds, indicating a broad ecological niche. The health effects associated with Helicobacter pylori strain ZH100 80 are significant, as it is linked to several gastrointestinal diseases. These include chronic gastric inflammation, gastric ulcers, and various forms of gastric cancer, such as adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. The strain is also implicated in more common conditions like GERD and functional dyspepsia. The pathogenicity of H. pylori strain ZH100 80 in humans underscores its role in chronic health issues, prompting a deeper understanding of its mechanisms and interactions within the gastrointestinal tract. This relationship between H. pylori and its human hosts highlights the importance of studying microbial strains not only for their pathogenic potential but also for their ecological roles in host health and disease dynamics.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain ZH100 80

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain ZH100 80
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH100 80, whole genome shotgun

Gene Summary

Adenine Count

494417 bp

Thymine Count

496721 bp

Guanine Count

318568 bp

Cytosine Count

312565 bp

Genome Length

1627857 bp

Protein-coding Genes

1487 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
restriction endonuclease subunit sEC550_07045Not AvailablePositive1420654 - 14207293042.73
outer membrane beta-barrel protein hoffEC550_07050Not AvailableNegative1421005 - 142250456805.0
abc transporter permeaseEC550_07055Not AvailableNegative1422784 - 142401646103.3
preprotein translocase subunit secaEC550_07060Not AvailableNegative1424006 - 142660399117.1
outer membrane lipoprotein chaperone lolaEC550_07065Not AvailablePositive1426751 - 142730521403.2
Tmrna,resume consensus sequence (at 77): aataactgtaaacaacacNot AvailableNot AvailablePositive1427367 - 1427751Not Available
hypothetical proteinEC550_07075Not AvailablePositive1427793 - 142832020055.0
outer membrane beta-barrel protein hofeEC550_07080Not AvailableNegative1428327 - 142969452016.8
is701 family transposaseEC550_07085Not AvailableNegative1429787 - 143107649382.9
hypothetical proteinEC550_07090Not AvailableNegative1431340 - 143161210317.7

Displaying genes 1331 – 1340 of 1529 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total