Helicobacter pylori strain ZH36 35

Helicobacter pylori strain ZH36 35 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and presence of flagella. This strain exhibits a single-cell arrangement and is classified as mesophilic, with an optimal growth temperature of 37°C. It is notable for having one replicon and two membranes, which is typical of bacteria with a Gram-negative cell structure. H. pylori strain ZH36 35 is primarily associated with various hosts, including Homo sapiens (humans), Gallus gallus (domestic chickens), Aves (birds), and several mammalian classes such as Primates and Rodentia. Its biotic relationship is categorized as free-living, indicating it can exist independently in its host environment. This strain is of significant medical importance due to its pathogenicity in humans. It is linked to a range of gastrointestinal diseases, including chronic gastric inflammation, peptic ulcer disease, and various forms of gastric cancer such as adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. Additionally, it can contribute to functional dyspepsia and conditions like GERD and hypochlorhydria. The relationship between H. pylori and its hosts underscores its role in human health, particularly regarding its potential to induce serious health issues. Understanding the pathogenic mechanisms of this strain may provide insights into the prevention and treatment of gastric diseases, highlighting the ecological relevance of H. pylori within both human and animal hosts.