Escherichia coli strain C15-b

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain C15-b is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. As a facultative anaerobe, it can thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, placing it within the mesophilic temperature range. This strain is characterized by a cell arrangement that includes both pairs and singles, and it possesses a single replicon and two membranes. C15-b is primarily associated with various hosts, including Homo sapiens, Gallus gallus, Bos taurus, and several other vertebrates and invertebrates. This extensive host range highlights its adaptability and potential for cross-species transmission. The strain is free-living, suggesting that it can survive outside of a host organism, which may contribute to its ecological versatility. The strain is notable for its pathogenic effects in humans, particularly related to urinary tract infections (UTIs) and gastrointestinal diseases. It is associated with a wide range of health issues, including peritonitis, neonatal meningitis, and foodborne infections. Specifically, it can lead to severe conditions such as hemolytic uremic syndrome (HUS), which is characterized by renal failure and can result from gastrointestinal infections. The diverse pathogenicity of E. coli strain C15-b underscores its significance in both human health and disease ecology. Its ability to inhabit various hosts while causing a multitude of health effects emphasizes the importance of monitoring this strain in clinical and environmental contexts. Understanding its interactions with different hosts and the environments they share can provide insights into transmission dynamics and infection control strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain C15-b

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain C15-b
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain C15-b NODE_119_length_1117_cov_70.372115,

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4318 genes

Non-Coding Genes

589 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Lytic tail proteinEFV08_03470Not AvailablePositive728164 - 72972058291.2
Trna-specific adenosine deaminaseEFV08_03475Not AvailableNegative729717 - 73025320027.3
phosphatidylglycerophosphatase cEFV08_03480Not AvailableNegative730278 - 73091324440.8
murr/rpir family transcriptional regulatorEFV08_03485Not AvailablePositive731122 - 73197030709.3
hypotheticalEFV08_03490Not AvailablePositive732002 - 7320732772.58
Hypothetical proteinEFV08_03495Not AvailablePositive732284 - 7325509903.79
hypothetical proteinEFV08_03500Not AvailablePositive732611 - 73325824272.4
Serine acetyltransferaseEFV08_03505Not AvailablePositive733620 - 73419221407.4
Qin prophageEFV08_03510Not AvailableNegative734236 - 73481421173.6
Tail fiberEFV08_03515Not AvailableNegative734814 - 73589037474.4

Displaying genes 1 – 10 of 4907 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total