Escherichia coli strain L889

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain L889 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and capable of mobility, possessing flagella. This strain thrives optimally at 37°C, placing it within the mesophilic temperature range. E. coli L889 exhibits a cell arrangement characterized by pairs and singles, and it has a unique biotic relationship, being free-living yet associated with a diverse range of hosts, including Homo sapiens, Gallus gallus, Bos taurus, and various other vertebrates and invertebrates. The health impacts of E. coli L889 are significant, as it is associated with various pathological conditions in humans. It can cause urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and septicemia, among other diseases. The strain is also linked to more severe outcomes such as hemolytic uremic syndrome (HUS), peritonitis, and even colorectal cancer. These health effects underscore the strain's potential as a pathogenic agent in both community and clinical settings. Given its wide range of hosts and ability to cause diverse infections, E. coli strain L889 illustrates the complex interplay between microbial pathogens and their hosts. Its pathogenicity highlights the importance of understanding bacterial behavior in relation to their environments and hosts, which is critical for developing effective prevention and treatment strategies for the diseases associated with this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain L889

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain L889
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain L889

Gene Summary

Adenine Count

1386626 bp

Thymine Count

1382639 bp

Guanine Count

1409391 bp

Cytosine Count

1412408 bp

Genome Length

5605530 bp

Protein-coding Genes

5216 genes

Non-Coding Genes

253 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
guanosine monophosphate reductaseD9K54_16430Not AvailablePositive3294578 - 329562137385.8
type iv pilin biogenesis proteinD9K54_16435Not AvailableNegative3295656 - 329685844418.2
type ii secretion system protein gspeD9K54_16440Not AvailableNegative3296848 - 329823350582.5
prepilin peptidase-dependent pilinD9K54_16445Not AvailableNegative3298243 - 329868315649.7
carboxylating nicotinate-nucleotide diphosphorylaseD9K54_16450Not AvailableNegative3298886 - 329977932774.0
1,6-anhydro-n-acetylmuramyl-l-alanine amidase ampdD9K54_16455Not AvailablePositive3299867 - 330041820509.2
protein ampeD9K54_16460Not AvailablePositive3300415 - 330126932123.9
aromatic amino acid transporter aropD9K54_16465Not AvailableNegative3301312 - 330268249547.9
pyruvate dehydrogenase complex repressorD9K54_16470Not AvailablePositive3303226 - 330399029427.2
pyruvate dehydrogenase (acetyl-transferring), homodimeric typeD9K54_16475Not AvailablePositive3304151 - 330681499674.1

Displaying genes 3231 – 3240 of 5469 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total