Escherichia coli strain CMSX59b

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain CMSX59b is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to the presence of flagella. This strain is adapted to a mesophilic environment, with an optimal growth temperature of 37°C. It typically exists in pairs or as singles, indicating a versatile cell arrangement. CMSX59b is associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and a wide range of other animals such as dogs, cats, and even some invertebrates like Apis mellifera (honeybees) and mollusks. This extensive host range highlights its ecological adaptability and potential for transmission across different species. The strain is known to cause significant health effects, prominently urinary tract infections (UTIs), gastrointestinal infections, and conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The wide array of diseases associated with CMSX59b underscores its pathogenic potential, particularly in humans, where it can lead to severe complications, including renal failure and sepsis. The biotic relationship of CMSX59b is classified as free-living, indicating that it can thrive independently in various environments, including those associated with its hosts. This adaptability may contribute to its role in both health and disease, as it can inhabit diverse ecological niches and engage in complex interactions with its hosts. Understanding the pathogenicity and ecological dynamics of CMSX59b is crucial for developing strategies to mitigate its health impacts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain CMSX59b

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain CMSX59b
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain CMSX59b NODE_2124, whole genome shotgun

Gene Summary

Adenine Count

1456567 bp

Thymine Count

1458766 bp

Guanine Count

1495280 bp

Cytosine Count

1486582 bp

Genome Length

6110873 bp

Protein-coding Genes

7095 genes

Non-Coding Genes

339 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinEAI42_05820Not AvailablePositive1089763 - 10899576804.24
Aaa family atpaseEAI42_05825Not AvailablePositive1090154 - 109158754186.9
hypothetical proteinEAI42_05830Not AvailablePositive1091580 - 109215221507.0
Putative portal proteinEAI42_05835Not AvailableNegative1092211 - 109323938886.5
GppEAI42_05840Not AvailableNegative1093239 - 109501166648.2
Capsid-scaffolding proteinEAI42_05845Not AvailablePositive1095185 - 109603931474.3
Capsid proteinEAI42_05850Not AvailablePositive1096098 - 109717140229.8
Terminase endonuclease subunitEAI42_05855Not AvailablePositive1097175 - 109791827461.6
Head completion/stabilization proteinEAI42_05860Not AvailablePositive1098018 - 109852719088.9
Tail proteinEAI42_05865Not AvailablePositive1098527 - 10987307053.42

Displaying genes 11 – 20 of 7434 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total