Escherichia coli strain CMJH98b

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain CMJH98b is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle, allowing it to thrive in various oxygen conditions. This strain is characterized by its mobility, attributed to the presence of flagella, and is typically found in host-associated habitats. It has a mesophilic temperature range, with an optimal growth temperature of 37°C. The strain is notable for its extensive biotic relationships, as it has been identified in a wide array of hosts, including Homo sapiens, Gallus gallus (chickens), Bos taurus (cattle), and various mammals, birds, and even plants like Solanum lycopersicum (tomato). Such diversity indicates its adaptability and potential for interaction across different ecosystems. E. coli CMJH98b is associated with numerous health complications, primarily in humans, including urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain's pathogenicity is particularly concerning in clinical settings, where it can lead to severe outcomes, including septicemia and renal failure. The presence of E. coli CMJH98b in diverse hosts and its ability to cause a range of infections underline its ecological significance. Its role in both free-living and pathogenic contexts highlights the delicate balance of microbial communities and their impact on host health and disease. Understanding these relationships is crucial for managing health risks associated with this bacterium in both human and veterinary medicine.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain CMJH98b

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain CMJH98b
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain CMJH98b NODE_2073, whole genome shotgun

Gene Summary

Adenine Count

1242564 bp

Thymine Count

1242962 bp

Guanine Count

1280493 bp

Cytosine Count

1272148 bp

Genome Length

5219583 bp

Protein-coding Genes

7105 genes

Non-Coding Genes

327 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Trna-argNot AvailableNot AvailablePositive5868825 - 5868899Not Available
hypothetical proteinEAI46_35600Not AvailableNegative5868975 - 586944217398.3
glutathione-dependent formaldehyde dehydrogenaseEAI46_35610Not AvailableNegative5870061 - 587064820969.2
hypothetical proteinEAI46_35615Not AvailableNegative5870679 - 587126621001.2
phosphopentomutaseEAI46_35620Not AvailablePositive5871297 - 587191322657.8
aldo/keto reductaseEAI46_35625Not AvailableNegative5871914 - 587253023253.6
preprotein translocaseEAI46_35630Not AvailableNegative5872531 - 587314624345.1
preprotein translocaseEAI46_35635Not AvailableNegative5873147 - 587376224345.1
yhch/yjgk/yial family proteinEAI46_35640Not AvailableNegative5873901 - 587435316924.4
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylaseEAI46_35650Not AvailableNegative5874995 - 58752157769.63

Displaying genes 6891 – 6900 of 7432 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total