Escherichia coli strain NGCE-33

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain NGCE-33 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in various oxygen conditions. It typically exists in pairs or singles and possesses flagella, enabling mobility. This strain is mesophilic, with an optimal growth temperature of 37°C, and has a single replicon and a double membrane structure. E. coli NGCE-33 is primarily associated with a wide range of hosts, including Homo sapiens, various livestock such as Bos taurus and Sus scrofa, and even plants like Solanum lycopersicum and Brassica oleracea var. italica. Its biotic relationship is classified as free-living, indicating its capability to exist independently in the environment. This strain is notable for its pathogenic potential in humans, being linked to numerous health effects, including urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and foodborne illnesses such as diarrhea and colibacillosis. The wide array of diseases associated with E. coli NGCE-33 underscores its significance as a public health concern, particularly in relation to infections that can lead to severe outcomes like hemolytic uremic syndrome (HUS) and septicemia. Ecologically, the presence of E. coli NGCE-33 in both animal and plant hosts suggests its adaptability and role in various ecological niches, potentially influencing microbial communities and health dynamics in both human and agricultural systems. Its association with diverse hosts highlights the importance of understanding this strain for addressing health and safety in both clinical and environmental contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain NGCE-33

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain NGCE-33
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain NGCE-33

Gene Summary

Adenine Count

1195292 bp

Thymine Count

1187071 bp

Guanine Count

1207922 bp

Cytosine Count

1226211 bp

Genome Length

4825635 bp

Protein-coding Genes

4440 genes

Non-Coding Genes

226 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinD6R52_03955Not AvailableNegative787067 - 78760320368.3
2-deoxyglucose-6-phosphate phosphataseD6R52_03960Not AvailablePositive787750 - 78841824330.7
metal-dependent hydrolaseD6R52_03965Not AvailablePositive788581 - 78917122351.7
l-cystine transporterD6R52_03970Not AvailablePositive789304 - 79069548713.8
hypothetical proteinD6R52_03975Not AvailableNegative790699 - 79150230097.4
cell division activator cedaD6R52_03980Not AvailableNegative791791 - 79205410201.5
catalase hpiiD6R52_03985Not AvailablePositive792237 - 79449884153.1
chitin disaccharide deacetylaseD6R52_03990Not AvailableNegative794545 - 79530328069.6
6-phospho-beta-glucosidaseD6R52_03995Not AvailableNegative795316 - 79666850427.3
arac family transcriptional regulatorD6R52_04000Not AvailableNegative796772 - 79761432999.4

Displaying genes 901 – 910 of 4682 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total