Corynebacterium propinquum strain HSID18034

Gram-positiveRodFacultative anaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Corynebacteriaceae

Genus

Corynebacterium

Description

Corynebacterium propinquum strain HSID18034 is a Gram-positive, rod-shaped bacterium that primarily resides in the nasopharynx and upper respiratory tract of Homo sapiens. As a facultative anaerobe, it can thrive in both aerobic and anaerobic environments, indicating its adaptability to various conditions within the human body. This strain is significant in clinical microbiology due to its association with several health conditions. It has been implicated in infective endocarditis, including both native and prosthetic valve infective endocarditis, as well as nosocomial infections and invasive diseases. Additionally, C. propinquum has been linked to respiratory tract infections and acute nongonococcal urethritis. These associations emphasize the potential pathogenicity of this bacterium, especially in individuals with compromised health. Corynebacterium propinquum strain HSID18034 has a single replicon and is cataloged under the accession number RBMC00000000.1, facilitating its identification and study in microbiological research. Understanding the ecological role of this bacterium in the upper respiratory tract may provide insights into its pathogenic mechanisms and its interaction with the human host, particularly in conditions that predispose individuals to infections. The presence of C. propinquum in the nasopharynx underscores the importance of monitoring bacterial communities in the upper respiratory tract, as they can influence health outcomes and the emergence of infectious diseases.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyCorynebacteriaceae
GenusCorynebacterium
SpeciesCorynebacterium propinquum
Strainstrain HSID18034

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Corynebacterium propinquum strain HSID18034
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatnasopharynx; NP; upper respiratory tract
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Corynebacterium propinquum strain HSID18034

Gene Summary

Adenine Count

602333 bp

Thymine Count

605268 bp

Guanine Count

782316 bp

Cytosine Count

807070 bp

Genome Length

2818253 bp

Protein-coding Genes

2570 genes

Non-Coding Genes

57 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
thiamine pyrophosphokinaseD8M20_00040Not AvailablePositive8026 - 921041930.0
copper transporterD8M20_00045Not AvailablePositive9210 - 1022633699.2
nudix hydrolaseD8M20_00050Not AvailablePositive10219 - 1097426637.1
site-specific tyrosine recombinase xerdD8M20_00055Not AvailablePositive10974 - 1190333746.0
hypothetical proteinD8M20_00060Not AvailablePositive12147 - 1245512037.2
hypothetical proteinD8M20_00065Not AvailablePositive12452 - 1287716165.1
para family proteinD8M20_00070Not AvailablePositive13085 - 1396031963.3
segregation/condensation protein aD8M20_00075Not AvailablePositive14035 - 1481729065.8
smc-scp complex subunit scpbD8M20_00080Not AvailablePositive14922 - 1552121872.8
rrna pseudouridine synthaseD8M20_00085Not AvailablePositive15551 - 1640831564.7

Displaying genes 11 – 20 of 2627 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

261 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001360methanesulfonateCH3O3SChemical structure of methanesulfonate59721-29-8
Average95.09Da
Monoisotopic94.980838711Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm0002197D-arabinoseC5H10O5Chemical structure of D-arabinoseNot available
Average150.1299Da
Monoisotopic150.05282343Da

Displaying 1–10 of 261 metabolites

Health Effects

Health ConditionRelationReference
Invasive diseaseCausesPMC12955418
Prosthetic valve endocarditisCausesPMC5116497
Native valve infective endocarditisCausesPMC5116497
Respiratory tract infectionsCausesPMC5116497
Acute nongonococcal urethritisCausesPMC5116497
Infective endocarditisCausesPMC5116497
Nosocomial infectionsCausesPMC5116497
Pulmonary infectionsCausesPMC7788810

Displaying health effects 1 – 8 of 8 in total