Moraxella catarrhalis strain COPD_M139

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Moraxellales

Family

Moraxellaceae

Genus

Moraxella

Description

Moraxella catarrhalis strain COPD_M139 is a Gram-negative bacterium that primarily inhabits host-associated environments. This strain exhibits a cocci shape and is classified as an aerobe, indicating that it requires oxygen for growth. It does not exhibit mobility, and while it possesses flagella, its lack of movement suggests that these structures may not play a significant role in its ecological niche. The strain is mesophilic, thriving in moderate temperature ranges, and has a single replicon, which is characteristic of its genome organization. Moraxella catarrhalis is known to have two membranes, typical of Gram-negative bacteria, providing a barrier that can affect interactions with the host and environmental factors. This bacterium has been identified in various hosts, including Homo sapiens (humans), Macaca mulatta (rhesus monkeys), and Chinchilla, indicating its adaptability to different biological environments. Moraxella catarrhalis strain COPD_M139 is associated with several health complications, notably respiratory infections, otitis media, and exacerbations of chronic obstructive pulmonary disease (COPD). It is implicated in various respiratory tract infections, including sinusitis and middle ear infections, particularly in children. The biotic relationship of Moraxella catarrhalis is classified as free-living, suggesting that it may exist independently in its environment but can also be opportunistic in causing infections in its hosts. This duality highlights its role in both human health as a pathogen and its ability to persist in diverse ecological niches. Understanding its characteristics can help inform treatment strategies for the infections it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderMoraxellales
FamilyMoraxellaceae
GenusMoraxella
SpeciesMoraxella catarrhalis
Strainstrain COPD_M139

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Moraxella catarrhalis strain COPD_M139
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Macaca mulatta, Chinchilla
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Moraxella catarrhalis strain COPD_M139

Gene Summary

Adenine Count

582887 bp

Thymine Count

582545 bp

Guanine Count

427357 bp

Cytosine Count

400503 bp

Genome Length

1993292 bp

Protein-coding Genes

1732 genes

Non-Coding Genes

133 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
atp-dependent dna helicase recgD6D91_00335Not AvailablePositive82462 - 8455876474.4
crp/fnr family transcriptional regulatorD6D91_00340Not AvailablePositive84551 - 8519824808.9
biotin/lipoyl-binding proteinD6D91_00345Not AvailablePositive85335 - 8584117609.9
hlyd family efflux transporter periplasmic adaptor subunitD6D91_00350Not AvailablePositive85851 - 8649222756.9
duf924 family proteinD6D91_00360Not AvailablePositive89820 - 9036520937.0
dephospho-coa kinaseD6D91_00365Not AvailableNegative90357 - 9099223225.1
prepilin peptidaseD6D91_00370Not AvailableNegative91144 - 9192028002.4
type ii secretion system f family proteinD6D91_00375Not AvailableNegative91920 - 9317945667.3
type iv-a pilus assembly atpase pilbD6D91_00380Not AvailableNegative93218 - 9488260919.8
bcr/cfla family efflux mfs transporterD6D91_00385Not AvailablePositive95037 - 9626044296.4

Displaying genes 181 – 190 of 1865 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
SinusitisCausesPMC12375837
Otitis mediaCausesPMC3695778
Respiratory infectionsCausesPMC3695778
Copd exacerbationCausesPMC7362441
Otitis mediaCausesPMC7362441
Respiratory tract infectionCausesPMC4765729
Childhood otitis mediaCausesPMC4765729
Respiratory tract infectionsCausesPMC4765729
Middle ear infectionsCausesPMC9318310
Copd-related infectionsCausesPMC3417516

Displaying health effects 1 – 10 of 22 in total