Streptococcus agalactiae strain JF4680

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus agalactiae strain JF4680 is a Gram-positive bacterium characterized by its cocci shape and arrangement in chains and pairs. It is a facultative anaerobe, indicating that it can thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, categorizing it as mesophilic. This strain lacks mobility and does not possess flagella, further defining its ecological niche. The bacterium is primarily host-associated, with documented biotic relationships that include free-living states. It has been found in various hosts, including humans (Homo sapiens), cattle (Bos taurus), and several fish species such as Oreochromis niloticus and Lates calcarifer. Due to its association with multiple hosts, it may play significant roles in both human and animal health. S. agalactiae strain JF4680 is known to be implicated in several serious health conditions, including bacteremia, pneumonia, meningitis, and necrotizing fasciitis in humans, as well as bovine mastitis in cattle. The bacterium is also associated with severe neonatal conditions such as neonatal meningitis and sepsis, highlighting its impact on vulnerable populations. Given its diverse host range and potential to cause significant health issues, Streptococcus agalactiae strain JF4680 is of considerable interest in microbiology and public health. Understanding its behavior and pathogenicity in various hosts is crucial for developing preventive measures and treatment strategies against its associated diseases.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus agalactiae
Strainstrain JF4680

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus agalactiae strain JF4680
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Bos taurus, Oreochromis niloticus
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus agalactiae strain JF4680 Contig91, whole genome

Gene Summary

Adenine Count

745925 bp

Thymine Count

730996 bp

Guanine Count

423823 bp

Cytosine Count

393009 bp

Genome Length

2293771 bp

Protein-coding Genes

2220 genes

Non-Coding Genes

147 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sensor histidine kinaseD5F95_01400Not AvailablePositive232560 - 23420963395.0
dna-binding response regulatorD5F95_01405Not AvailablePositive234213 - 23498630147.5
extracellular solute-binding proteinD5F95_01410Not AvailablePositive234998 - 23603538179.0
zeta toxinD5F95_01415Not AvailableNegative236257 - 23675419125.1
m42 family peptidaseD5F95_01420Not AvailableNegative236754 - 23779138211.2
class ib ribonucleoside-diphosphate reductase assembly flavoprotein nrdiD5F95_01425Not AvailableNegative237802 - 23825716800.9
bifunctional (p)ppgpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolaseD5F95_01435Not AvailablePositive241075 - 24329184213.1
d-tyrosyl-trna(tyr) deacylaseD5F95_01440Not AvailablePositive243301 - 24374415953.0
adhesion proteinD5F95_01445Not AvailablePositive243999 - 24492234018.9
pneumococcal-type histidine triad proteinD5F95_01450Not AvailablePositive244949 - 24753196322.7

Displaying genes 361 – 370 of 2367 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC11116026
Neonatal meningitisCausesPMC11116026
SepsisCausesPMC11286787
Streptococcal toxic shock syndrome (stss)CausesPMC11735781
Necrotizing fasciitisCausesPMC11735781
MeningitisCausesPMC11735781
Acute rheumatic fever (arf)CausesPMC11735781
Bovine mastitisCausesPMC13280230
MastitisCausesPMC13280230
Udder infectionsCausesPMC13373013

Displaying health effects 1 – 10 of 21 in total