Escherichia coli strain HR135

Escherichia coli strain HR135 is a Gram-negative, rod-shaped bacterium that exhibits facultative anaerobic metabolism, allowing it to thrive in various environments. This strain is motile, possessing flagella, and typically arranges itself in pairs or as single cells. It is mesophilic, with an optimal growth temperature of 37°C. Strain HR135 is free-living and associated with a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other vertebrates and invertebrates, indicating its versatile ecological niche. The bacterium has been implicated in a multitude of health effects, particularly in humans, where it is associated with urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis, among others. Its pathogenic potential is highlighted by its role in severe conditions such as hemolytic uremic syndrome (HUS) and septicemia. These health impacts underscore the strain's significance in both clinical and environmental microbiology. The diverse host range of E. coli strain HR135 reveals its adaptability and potential for cross-species transmission, which is an important factor in understanding its ecology and evolution. The strain's capacity to cause a variety of serious health issues further emphasizes the need for ongoing surveillance and research to mitigate risks associated with this bacterium in both human and animal populations.