Escherichia coli strain S308

Escherichia coli strain S308 is a Gram-negative, rod-shaped bacterium that belongs to the family Enterobacteriaceae. This strain is facultatively anaerobic, allowing it to thrive in varying oxygen conditions, and is motile due to the presence of flagella. It is a mesophilic organism with an optimal growth temperature of 37°C and typically arranges itself in pairs or singles. E. coli S308 is primarily host-associated, demonstrating a free-living biotic relationship with a diverse range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other vertebrates and invertebrates. The strain has been associated with numerous health effects, notably including urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. It is implicated in severe conditions such as hemolytic uremic syndrome (HUS), peritonitis, and foodborne diseases, alongside various other clinical manifestations like diarrhea, renal failure, and colibacillosis. The extensive host range and pathogenic potential of E. coli S308 highlight its ecological versatility and adaptability in different environments. Its association with both humans and a variety of animal hosts underscores its role in zoonotic transmission and the public health implications of fecal contamination in food and water sources. Understanding the pathogenic mechanisms and ecological interactions of this strain is crucial for addressing its impact on health and disease.