Clostridium botulinum strain CDC66008

Gram-positiveRodMotileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Clostridiaceae

Genus

Clostridium

Description

Clostridium botulinum strain CDC66008 is a notable anaerobic, Gram-positive bacterium characterized as a mesophilic rod that thrives optimally at 37°C. This strain is a chemoorganotroph, utilizing organic compounds as its energy source. The cells can be found in various arrangements, including pairs, singles, and chains, and they are motile due to the presence of flagella. C. botulinum strain CDC66008 is primarily free-living, but it has significant health implications for humans, including the potential to cause wound botulism and botulism. Its pathogenicity is linked to the production of botulinum toxin, which poses serious health risks. This strain has a single replicon and a single membrane. Understanding the ecological niche of C. botulinum is crucial, as it can be found in multiple habitats, which may include soil, water, and decaying organic matter. Its anaerobic nature allows it to thrive in environments devoid of oxygen, providing insights into its survival strategies and potential interactions within various ecosystems. The relationship of C. botulinum with its human hosts highlights the dual nature of microorganisms, where some can be beneficial while others pose significant health risks. This underscores the importance of studying such strains to mitigate their impact on public health while appreciating their ecological roles.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyClostridiaceae
GenusClostridium
SpeciesClostridium botulinum
Strainstrain CDC66008

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Clostridium botulinum strain CDC66008
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Bos, Metazoa
Cell arrangementPairs - Singles - Chains
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Clostridium botulinum strain CDC66008

Gene Summary

Adenine Count

1501389 bp

Thymine Count

1498305 bp

Guanine Count

579555 bp

Cytosine Count

583054 bp

Genome Length

4162303 bp

Protein-coding Genes

3160 genes

Non-Coding Genes

120 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
murr/rpir family transcriptional regulatorDZC34_13785Not AvailableNegative2587585 - 258834628917.0
nad-dependent epimerase/dehydratase family proteinDZC34_13790Not AvailableNegative2588784 - 258942223186.9
dsba family proteinDZC34_13795Not AvailableNegative2589449 - 259005423193.9
rrf2 family transcriptional regulatorDZC34_13800Not AvailableNegative2590154 - 259063617751.9
duf1003 domain-containing proteinDZC34_13805Not AvailableNegative2591071 - 259162521214.7
cold-shock proteinDZC34_13810Not AvailableNegative2592047 - 25922447112.25
hypothetical proteinDZC34_13815Not AvailablePositive2592513 - 25926957137.72
pts glucose transporter subunit iiaDZC34_13825Not AvailableNegative2593797 - 259430618438.3
6-phospho-alpha-glucosidaseDZC34_13830Not AvailableNegative2594490 - 259581550009.4
pts glucose transporter subunit iibcDZC34_13835Not AvailableNegative2596131 - 259770256732.8

Displaying genes 2071 – 2080 of 3280 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Wound botulismCausesPMC8283217
BotulismCausesPMC2693436
BotulismCausesPMC13317340
BotulismCausesPMC3232984
BotulismCausesPMC5113727
BotulismCausesPMC7904509

Displaying health effects 1 – 6 of 6 in total