Clostridium botulinum strain CDC66008

Gram-positiveRodMotileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Clostridiaceae

Genus

Clostridium

Description

Clostridium botulinum strain CDC66008 is a notable anaerobic, Gram-positive bacterium characterized as a mesophilic rod that thrives optimally at 37°C. This strain is a chemoorganotroph, utilizing organic compounds as its energy source. The cells can be found in various arrangements, including pairs, singles, and chains, and they are motile due to the presence of flagella. C. botulinum strain CDC66008 is primarily free-living, but it has significant health implications for humans, including the potential to cause wound botulism and botulism. Its pathogenicity is linked to the production of botulinum toxin, which poses serious health risks. This strain has a single replicon and a single membrane. Understanding the ecological niche of C. botulinum is crucial, as it can be found in multiple habitats, which may include soil, water, and decaying organic matter. Its anaerobic nature allows it to thrive in environments devoid of oxygen, providing insights into its survival strategies and potential interactions within various ecosystems. The relationship of C. botulinum with its human hosts highlights the dual nature of microorganisms, where some can be beneficial while others pose significant health risks. This underscores the importance of studying such strains to mitigate their impact on public health while appreciating their ecological roles.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyClostridiaceae
GenusClostridium
SpeciesClostridium botulinum
Strainstrain CDC66008

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Clostridium botulinum strain CDC66008
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Bos, Metazoa
Cell arrangementPairs - Singles - Chains
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Clostridium botulinum strain CDC66008

Gene Summary

Adenine Count

1501389 bp

Thymine Count

1498305 bp

Guanine Count

579555 bp

Cytosine Count

583054 bp

Genome Length

4162303 bp

Protein-coding Genes

3160 genes

Non-Coding Genes

120 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
class i sam-dependent methyltransferaseDZC34_11545Not AvailableNegative2154533 - 215571145998.5
rrf2 family transcriptional regulatorDZC34_11555Not AvailablePositive2157646 - 215806815742.9
vrr-nuc domain-containing proteinDZC34_11560Not AvailablePositive2158229 - 21584106596.12
polymer-forming cytoskeletal proteinDZC34_11575Not AvailablePositive2159018 - 215990832902.5
zinc ribbon domain-containing proteinDZC34_11580Not AvailablePositive2159971 - 216038716190.6
Trna-trpNot AvailableNot AvailablePositive2160552 - 2160627Not Available
fad-binding proteinDZC34_11590Not AvailablePositive2160868 - 216208244554.1
trna (adenosine(37)-n6)-threonylcarbamoyltransferase complex transferase subunit tsadDZC34_11600Not AvailablePositive2163346 - 216436836581.1
pyruvate carboxylaseDZC34_11605Not AvailablePositive2164827 - 2168261127936.0
insulinase family proteinDZC34_11610Not AvailablePositive2168643 - 2171570113640.0

Displaying genes 1741 – 1750 of 3280 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Wound botulismCausesPMC8283217
BotulismCausesPMC2693436
BotulismCausesPMC13317340
BotulismCausesPMC3232984
BotulismCausesPMC5113727
BotulismCausesPMC7904509

Displaying health effects 1 – 6 of 6 in total