Bacteroides fragilis strain OF05-11AC

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis strain OF05-11AC is a Gram-negative, anaerobic, rod-shaped bacterium that belongs to the Bacteroides genus. This strain is classified as a chemoorganotroph, deriving energy from organic compounds, and is typically found in host-associated environments. It possesses a single chromosome and has a distinctive double membrane structure. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range. This bacterium is non-motile and does not have flagella, indicating that it does not move independently. Bacteroides fragilis strain OF05-11AC is free-living but has been identified in association with various hosts, including Homo sapiens, Gallus gallus (chickens), Metazoa, Equidae (horses), and Serpentes (snakes). Bacteroides fragilis is known for its pathogenic potential in humans, being associated with a range of health complications such as bacteremia, abscesses, Alzheimer's disease pathologies, diarrhea, colitis, septicemia, colorectal cancer, tumor formation, and soft-tissue infections. The presence of this bacterium in the human microbiome highlights its dual role as a part of normal flora while also posing significant health risks under certain conditions. The ecological insight gleaned from Bacteroides fragilis strain OF05-11AC's traits is its adaptability and potential impact on both host health and disease, emphasizing the importance of understanding microbial interactions within various host environments.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
Strainstrain OF05-11AC

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis strain OF05-11AC
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain OF05-11AC OF05-11AC.Scaf30, whole

Gene Summary

Adenine Count

1543972 bp

Thymine Count

1504460 bp

Guanine Count

1141577 bp

Cytosine Count

1208714 bp

Genome Length

5398873 bp

Protein-coding Genes

4621 genes

Non-Coding Genes

102 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
trna(5-methylaminomethyl-2-thiouridine)- methyltransferaseDXA78_02215Not AvailableNegative519374 - 52043539659.3
o-acetylhomoserine aminocarboxypropyltransferase/cysteine synthaseDXA78_02220Not AvailableNegative520440 - 52172646133.9
hypothetical proteinDXA78_02225Not AvailableNegative521730 - 5219398391.24
duf4595 domain-containing proteinDXA78_02230Not AvailablePositive521896 - 52272030758.4
esterase family proteinDXA78_02235Not AvailableNegative522937 - 52375530709.9
duf2007 domain-containing proteinDXA78_02240Not AvailableNegative523787 - 52422416163.4
tonb-dependent receptorDXA78_02245Not AvailablePositive524331 - 52670388352.1
peptidase m48DXA78_02250Not AvailablePositive526745 - 52754528785.4
hlyc/corc family transporterDXA78_02255Not AvailablePositive527702 - 52899148271.0
copper homeostasis proteinDXA78_02260Not AvailablePositive529043 - 52950116252.3

Displaying genes 481 – 490 of 4723 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total