Bacteroides fragilis strain OM04-9BH

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis strain OM04-9BH is a Gram-negative, rod-shaped anaerobe that thrives in host-associated environments. This strain is classified as a chemoorganotroph, deriving energy from organic compounds, and exhibits a mesophilic temperature range with an optimal growth temperature of 37°C. Importantly, this bacterium is non-motile and is characterized by its single-cell arrangement and the presence of two membranes, with one replicon in its genome. This strain has been identified in various hosts, including Homo sapiens (humans), Gallus gallus (chickens), Metazoa (multicellular animals), Equidae (horses), and Serpentes (snakes). Its biotic relationship is categorized as free-living, indicating its ability to survive independently within these hosts. Bacteroides fragilis strain OM04-9BH is notable for its pathogenicity in humans, where it is associated with a range of health issues including bacteremia, abscesses, colitis, and colorectal cancer. The strain's ability to cause anaerobic bacteremia and local tissue infections highlights its potential impact on human health, particularly in immunocompromised individuals or those with underlying conditions. Ecologically, this strain plays a significant role in the microbiota of various hosts, contributing to the complex interactions within their respective ecosystems. Its pathogenic potential and association with diverse hosts underscore its importance in both health and disease contexts, reflecting the intricate balance between microbial inhabitants and their hosts.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
Strainstrain OM04-9BH

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis strain OM04-9BH
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain OM04-9BH OM04-9BH.Scaf43, whole genome

Gene Summary

Adenine Count

1549660 bp

Thymine Count

1533867 bp

Guanine Count

1177936 bp

Cytosine Count

1198233 bp

Genome Length

5459886 bp

Protein-coding Genes

4520 genes

Non-Coding Genes

89 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
gntr family transcriptional regulatorDXB57_08585Not AvailableNegative1899475 - 190045237669.1
glycoside hydrolase family 127 proteinDXB57_08590Not AvailablePositive1900681 - 190275076953.9
duf1080 domain-containing proteinDXB57_08595Not AvailablePositive1902722 - 190517892462.2
m20/m25/m40 family metallo-hydrolaseDXB57_08600Not AvailableNegative1905548 - 190660939030.8
long-chain fatty acid--coa ligaseDXB57_08605Not AvailablePositive1906799 - 190860468314.5
pcrf domain-containing proteinDXB57_08610Not AvailablePositive1908665 - 190978142572.1
hypothetical proteinDXB57_08615Not AvailableNegative1909929 - 191079833878.5
rna polymerase sigma-70 factorDXB57_08625Not AvailablePositive1911477 - 191207623238.9
fecr family proteinDXB57_08630Not AvailablePositive1912484 - 191340135029.3
susc/raga family tonb-linked outer membrane proteinDXB57_08635Not AvailablePositive1913496 - 1916894125457.0

Displaying genes 1661 – 1670 of 4609 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total